Sökning: "OXIDATIVE DNA-DAMAGE"

Visar resultat 11 - 15 av 46 avhandlingar innehållade orden OXIDATIVE DNA-DAMAGE.

1. 11. Assessment of DNA damage, oxidative stress and inflammation in chronic kidney disease patients : and a clinical study of a dietary supplement

   Författare :Ylva Rodhe; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Decreased kidney function is associated with higher levels of oxidative stress, inflammation and malnutrition. Chronic kidney disease (CKD) patients have a higher risk to develop cardiovascular disease, atherosclerosis and cancer compared to the general population. Cardiovascular disease is the major cause of death in CKD patients. LÄS MER

3. 12. Role of oxidative stress response in radiosensitivity

   Författare :Ali Pour Khavari; Siamak Haghdoost; Bo Stenerlöw; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Oxidative stress; radiosensitivity; 8-oxo-dG; DNA-repair; NRF2; glioblastoma; radiotherapy; molekylär biovetenskap; Molecular Bioscience;

   Sammanfattning : The quality of the ionizing radiation (IR) can be described in terms of its nature, photons or particles, and their corresponding energies. The energy is classified in terms of High or Low linear energy transfer that will produce a different distribution of DNA damage and other molecules in the cell either by direct action or indirect action. LÄS MER

4. 13. Particularly harmful particles? A study of airborne particles with a focus on genotoxicity and oxidative stress

   Författare :Hanna Karlsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :particulate matter; particles; genotoxicity; oxidative stress; DNA damage; inflammation; subway; tire-road; wood;

   Sammanfattning : Today it is well established that particulate matter (PM) cause a wide range of health effects. The underlying mechanisms likely include inflammation, oxidative stress and genotoxicity. There is however a lack of knowledge regarding how particles from different sources contribute to these effects. LÄS MER

5. 14. Altered gene expression in the human airways during oxidative stress

   Författare :Tiziana Dandrea; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Nitrogen dioxide; Ozone; Oxidative stress; Gene expression; Redox signalling; GSH; Alveolar macrophages.;

   Sammanfattning : The atmospheric accumulation of pollutant gases, such as N02 and ozone, has been associated with an increased airways hyper-reactivity within the healthy population. Moreover, those with conditions such as asthma and chronic obstructive pulmonary diseases generally experience an exacerbation of their symptoms upon exposure to these noxious gases. LÄS MER

7. 15. Short and long-term effects of exposure to low dose and low dose rate of gamma radiation : using in vitro and in vivo models

   Författare :Traimate Sangsuwan; Siamak Haghdoost; Eva Forssell-Aronsson; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Low dose; Low dose rate; High dose rate; Ionizing radiation; Adaptive response; Senescence; Premature senescence; Oxidative stress; Drosophila embryo; Mutation; DNA repair; molekylär biovetenskap; Molecular Bioscience;

   Sammanfattning : Assessment of human health risks from exposure to ionizing radiation (IR) is mainly based on the extrapolation of results from epidemiological studies on populations exposed to relatively high doses and often at high dose rates (HDR). Risk estimates after exposure to low doses and in particular at low dose rates (LDR) remain controversial due to a lack of epidemiological evidence. LÄS MER