Sökning: "Metabolic approach"

Visar resultat 16 - 20 av 260 avhandlingar innehållade orden Metabolic approach.

  1. 16. Processing and analysis of NMR data : Impurity determination and metabolic profiling

    Författare :Jenny Forshed; Sven P. Jacobsson; Jules L. Griffin; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; quantitative nuclear magnetic resonance spectrometry; qNMR; multivariate analysis; peak alignment; data fusion; Analytical chemistry; Analytisk kemi;

    Sammanfattning : This thesis describes the use of nuclear magnetic resonance (NMR) spectrometry as an analytical tool. The theory of NMR spectroscopy in general and quantitative NMR spectrometry (qNMR) in particular is described and the instrumental properties and parameter setups for qNMR measurements are discussed. LÄS MER

  3. 17. Novel Synthetic Biology Tools for Metabolic Engineering of Saccharomyces cerevisiae

    Författare :Siavash Partow; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Yeast promoter; MVA pathway; Metabolic engineering; Multi-copy plasmid.; Synthetic biology; S. cerevisiae; MEP pathway;

    Sammanfattning : The most well characterized eukaryote model organism Saccharomyces cerevisiae is not only preferred as a microbial cell factory for synthesis of industrial products, e.g. bioethanol, but this eukaryote host system is also defined as a robust scaffold for commercial production of diverse chemicals e.g. LÄS MER

  4. 18. The stochastic nature of intracellular control circuits

    Författare :Johan Paulsson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Stochastic; mesoscopic; noise; gene; plasmid; metabolic; regulation; control; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Chemical reactions are probabilistic by nature, causing random fluctuations inconcentrations to emerge spontaneously. In conventional (macroscopic) kinetics this internal noise is ignored under the assumption that average copy numbers are so high that fluctuations are negligible in comparison. LÄS MER

  5. 19. Mathematical Modelling of Cerebral Metabolism : From Ion Channels to Metabolic Fluxes

    Författare :Nicolas Sundqvist; Gunnar Cedersund; Maria Engström; Roland Nilsson; Sebastian Sten; João Duarte; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The brain is the most metabolically active organ in the human body and therefore rely on a continuous supply of oxygen and glucose. Neuronal stimulation in specific regions of the leads to the firing of action potentials, a process facilitated by voltage-gated ion channels in the neurons’ cell membranes. LÄS MER

  7. 20. Combining Metabolic Engineering and Synthetic Biology Approaches for the Production of Abscisic Acid in Yeast

    Författare :Maximilian Otto; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; metabolic engineering; Botrytis cinerea; cell factory; abscisic acid; synthetic biology; biosensor; sesquiterpenoid; standardization; Saccharomyces cerevisiae;

    Sammanfattning : Nature presents us with a myriad of complex and diverse molecules. Many of these molecules prove to be useful to humans and find applications as pharmaceuticals, biofuels, agrochemicals, cosmetic ingredients or food additives. One highly promising natural product with a broad range of potential applications is the terpenoid abscisic acid (ABA). LÄS MER