Sökning: "Meningococcal Disease"

Visar resultat 6 - 10 av 15 avhandlingar innehållade orden Meningococcal Disease.

  1. 6. Analysis of Complement Deficiency States. With Focus on Molecular Characterization of C4 and Properdin Deficiency

    Författare :Gunilla Nordin Fredrikson; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mycology; virology; bacteriology; Complement C4; Complement; Complement Screening; Deficiency; Meningococcal Disease; Properdin; Properdin Expression; Microbiology; Sequencing; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Complement deficiency is associated with an increased risk for invasive infection and immune complex disease. Screening for identification of complement-deficient patients is essential and a new ELISA-based procedure for detection of complement deficiency is described. LÄS MER

  3. 7. Molecular studies of Neisseria : host cell interactions

    Författare :Anne Rytkönen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The Neisseria family includes many non-pathogenic species but also two strict human pathogens; Neisseria gonorrhoeae and Neisseria meningitidis. Both organisms colonise mucosal surfaces and may cause disseminated infections upon passage of the epithelial barrier. LÄS MER

  4. 8. Virulence Factors and Motility Mechanisms of Pathogenic Neisseria

    Författare :Jens Eriksson; Ann-Beth Jonsson; Helena Aro; Tone Tønjum; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neisseria; Virulence factors; Type IV pili; PilT; PilU; NafA; NhhA; Twitching motility; molekylärgenetik; Molecular Genetics;

    Sammanfattning : Neisseria gonorrhoeae and Neisseria meningitidis are two closely related human specific pathogens. Neisseria gonorrhoeae is the causative agent for the sexually transmitted disease gonorrhea and often causes asymptomatic infections in women which is a cause of infertility. LÄS MER

  5. 9. Pathogenic Neisseria : Single cell motility, multicellular dynamics and antimicrobial susceptibility

    Författare :Olaspers Sara Eriksson; Ann-Beth Jonsson; Matthew Francis; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neisseria; Type IV pili; Twitching motility; PilT; Microcolony dynamics; PilU; NafA; Antimicrobial peptide; Cell-penetrating peptide; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Neisseria meningitidis and Neisseria gonorrhoeae can colonize humans without causing any symptoms. However, gonorrhea and invasive meningococcal disease are serious health concerns. An essential virulence factor for neisserial adhesion to host cells, twitching motility and microcolony formation/aggregation is the retractile type IV pili (Tfp). LÄS MER

  7. 10. Receptor Interactions Between Pathogenic Bacteria and Host Cells

    Författare :Lena Lövkvist; Ann-Beth Jonsson; Heiko Herwald; Uppsala universitet; []
    Nyckelord :Microbiology; Type IV pili; Lipooligosaccharide; ScpC protease; CD46; Mikrobiologi;

    Sammanfattning : This thesis focuses on host and pathogen specific interactions during invasive disease. We have investigated the role and impact of different virulence factors of Neisseria gonorrhoeae, N. meningitidis and Streptococcus pyogenes on host epithelial cells and in vivo. N. LÄS MER