Sökning: "Complement Screening"

Visar resultat 1 - 5 av 60 avhandlingar innehållade orden Complement Screening.

  1. 1. Analysis of Complement Deficiency States. With Focus on Molecular Characterization of C4 and Properdin Deficiency

    Författare :Gunilla Nordin Fredrikson; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mycology; virology; bacteriology; Complement C4; Complement; Complement Screening; Deficiency; Meningococcal Disease; Properdin; Properdin Expression; Microbiology; Sequencing; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Complement deficiency is associated with an increased risk for invasive infection and immune complex disease. Screening for identification of complement-deficient patients is essential and a new ELISA-based procedure for detection of complement deficiency is described. LÄS MER

  3. 2. Aspects of Complement Activation in Thrombocytopenic Disorders

    Författare :Alexander Åkesson; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thrombocytopenia; Complement activation; Complement dysregulation; Thrombotic microangiopathy; Atypical hemolytic uremic syndrome; Platelet transfusion refractoriness;

    Sammanfattning : The complement system is an essential effector of both innate and acquired immune responses. Due to its destructive potential, tight regulation is required. The contribution of complement has been associated with the pathogeneses in a wide range of diseases. LÄS MER

  4. 3. Human adenoviruses : new bioassays for antiviral screening and CD46 interaction

    Författare :Emma Andersson; Göran Wadell; Sigvard Olofsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adenovirus; CD46; hemagglutination; antiviral; small molecule; screening; Virology; Virologi;

    Sammanfattning : Adenoviruses are common pathogens all over the world. The majority of the population has at some point been infected with an adenovirus. Although severe disease can occur in otherwise healthy individuals an adenovirus infection is most commonly self limited in these cases. LÄS MER

  5. 4. Computational Methods in Medicinal Chemistry : Mechanistic Investigations and Virtual Screening Development

    Författare :Fredrik Svensson; Christian Sköld; Anders Karlén; Anna Linusson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; DFT; IRAP; Virtual Screening; Catalysis; Palladium; Medicinal Chemistry; Läkemedelskemi;

    Sammanfattning : Computational methods have become an integral part of drug development and can help bring new and better drugs to the market faster. The process of predicting the biological activity of large compound collections is known as virtual screening, and has been instrumental in the development of several drugs today in the market. LÄS MER

  7. 5. ETHICS AND PUBLIC HEALTH INTERVENTIONS

    Författare :Ingela Krantz; Medicinsk etik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Herpes virus type 2; prostate cancer; measles; evidence-based medicine; casuistry; virtues; principlism; values; ethics; vaccination; Public health; screening; postpartum depression.;

    Sammanfattning : Programmatic vaccination and screening are the reasons for this thesis. The practice of public health incorporating medicine’s cognitive contents along with contributions from other fields of human activities is basically a moral enterprise. LÄS MER