Sökning: "KIR"

Visar resultat 11 - 15 av 27 avhandlingar innehållade ordet KIR.

  1. 11. Natural killer cells and antibody-mediated effects in human immunodeficiency virus infection

    Författare :Susanne Johansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The human immunodeficiency virus (HIV-1) effectively avoids immunologic eradication. Certain characteristics of the virus contribute to this, including the specific targeting of the body s own defense system, the ability to hide in the host cell genome and the vast viral variability. LÄS MER

  3. 12. Natural killer cell development and function in the context of allogenic stem cell transplantation and cell therapy

    Författare :Alvaro Haroun-Izquierdo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Natural killer (NK) cells play a crucial role in the control of viral infections and transformed, cancerous cells. These innate cells have high cytotoxic capacities and use a multitude of receptors to interact with neighbouring cells. LÄS MER

  4. 13. Intercellular protein transfer and regulation of inhibitory NK receptor accessibility

    Författare :Katja Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : NK cells are important players of innate immunity and capable of promoting specific responses of the adaptive immune system. NK cells possess the ability to recognise and eliminate virus-infected cells, tumour cells and allogeneic bone marrow grafts. LÄS MER

  5. 14. Vasodilator actions of EDHF and anandamide

    Författare :David Andersson; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vanilloid receptors; afferent neurons; anandamide; cannabinoids; potassium channels; hyperpolarization; vasodilation; Vascular endothelium; arteries; airways; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Sammanfattning : Vasodilator responses to endothelium-derived hyperpolarizing factor (EDHF) and anandamide in isolated arteries were investigated. A combination of the potassium channel blockers charybdotoxin and apamin inhibits EDHF-mediated relaxations. LÄS MER

  7. 15. Immunological responses in genital HPV infections and etiology of cervical cancer

    Författare :Lisen Arnheim; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HPV; CIN; cervical cancer; antibodies; KIRs; CXCL8; IFN-gamma; Chlamydia trachomatis;

    Sammanfattning : Cervical cancer is one of the most common forms of cancers in women. Every year approximately 450,000 women are diagnosed worldwide and 200,000 die. The sexually transmitted oncogenic human papillomavirus (HPV) types are established as the major etiological agents of cancer of the cervix. LÄS MER