Sökning: "Jaundice"

Visar resultat 6 - 10 av 15 avhandlingar innehållade ordet Jaundice.

  1. 6. Insulin resistance in pancreatic cancer

    Författare :Bengt Isaksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Pancreatic cancer; glucose transport; glucose metabolism; insulin signaling; insulin resistance; uncoupling proteins; obstructive jaundice; IAPP; risk factors.;

    Sammanfattning : The dismal prognosis of pancreatic cancer (PC) is related to metabolic complications of the tumor. Impaired glucose tolerance or diabetes due to insulin resistance, and cachexia are observed early and frequently in these patients. The basic mechanisms of PC-associated insulin resistance and weight loss are not fully understood. LÄS MER

  3. 7. Etiological insights into the testicular cancer epidemic

    Författare :Olof Akre; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Testicular neoplasms; seminoma; nonseminoma; epidemiology; etiology; risk factors; prenatal; fertility; birth weight; placenta; neonatal jaundice; cryptorchidism; hypospadias; preterm birth; Epstein-Barr virus; cytomegalovirus; Body Mass Index; height;

    Sammanfattning : The aim of this thesis was to search for causes of the testicular cancer epidemic through epidemiologic studies of testicular cancer and possibly related conditions, such as urogenital birth defects and subfertility. First, we assessed changes in fertility over time by studying time-to-pregnancy among primiparous women in Sweden from 1983 through 1993 using data from the Medical Birth Registry. LÄS MER

  4. 8. Genetic studies of familial hemophagocytic lymphohistiocytosis

    Författare :Kim Göransdotter Ericson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Familial hemophagocytic lymphohistiocytosis FHL ; PRF1 gene; MUNC13-4 gene; NK cells; cytotoxic T lymphocytes;

    Sammanfattning : The main contribution from this thesis is a refined knowledge of locus heterogeneity in familial hernophagocytic lympbohistiocytosis (FHL) and a further characterization of corresponding clinical and immunological phenotypes. Familial hemophagocytic lymphohistiocytosis is a fatal autosomal recessive immune deficiency clinically characterized by fever, cytopenia, hepatosplenomegaly, and hemophagocytosis. LÄS MER

  5. 9. Incidental Gallbladder Cancer : Incidence, predictors, management and outcome in a Swedish population

    Författare :Linda Lundgren; Per A Sandström; Axel Ros; Gunnar Persson; Oliver Gimm; Magnus Nilsson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Background: Cholecystectomy is a common surgical procedure and incidental gallbladder cancer is a rare and unexpected finding at a cholecystectomy performed upon benign indications. Whether to perform routine or selective histopathology of the gallbladder specimen is still a subject for discussion. LÄS MER

  7. 10. Primary biliary cirrhosis : an epidemiological and clinical study based on patients from northern Sweden

    Författare :Per Uddenfeldt; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Primary biliary cirrhosis; incidence; prevalence; disease course; Kveim test; sarcoidosis; rheumatic disorders; lung function; diffusing capacity; Sjögren syndrome; von Willebrand factor;

    Sammanfattning : Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease, which primarily affects middle-aged women. The liver histology is characterized by inflammation and destruction of the intrahepatic bile ducts as well as a high frequency of granuloma. LÄS MER