Sökning: "rheumatic disorders"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden rheumatic disorders.

  1. 1. Primary biliary cirrhosis : an epidemiological and clinical study based on patients from northern Sweden

    Författare :Per Uddenfeldt; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Primary biliary cirrhosis; incidence; prevalence; disease course; Kveim test; sarcoidosis; rheumatic disorders; lung function; diffusing capacity; Sjögren syndrome; von Willebrand factor;

    Sammanfattning : Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease, which primarily affects middle-aged women. The liver histology is characterized by inflammation and destruction of the intrahepatic bile ducts as well as a high frequency of granuloma. LÄS MER

  3. 2. Understanding inflammatory mechanisms in rheumatic diseases

    Författare :Ia Khmaladze; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Rheumatoid arthritis (RA), Psoriasis (Ps) and Psoriasis arthritis (PsA) are chronic inflammatory autoimmune disorders, where primary targets are peripheral joints, skin and skin/joints respectively. Both innate and adaptive immunity play a role in disease initiation and progression. LÄS MER

  4. 3. Cardiac Performance, Ventricular-Vascular Interaction and Functional Alterations in Rheumatic Mitral Stenosis : A descriptive study employing novel hemodynamic and echocardiographic modalities

    Författare :Ashwin Venkateshvaran; Lars-Åke Brodin; Per Lindquist; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Tillämpad medicinsk teknik; Applied Medical Technology;

    Sammanfattning : The assessment of LV performance poses significant challenges in the setting of rheumatic mitral stenosis (MS) owing to an inherently load-altered state. A detailed characterization of arterial-ventricular coupling between subjects with isolated post-capillary pulmonary hypertension (Ipc-PH) and combined pre- and post-capillary pulmonary hypertension (Cpc-PH) has not been described. LÄS MER

  5. 4. Mixed connective tissue disease, myositis and systemic lupus erythematosus : immunological and genetic studies in three related rheumatic autoimmune studies

    Författare :Adla Bakri Hassan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MCTD; SLE; PM DM; autoantibodies; cytokines; MHC; polymorphisms.;

    Sammanfattning : Mixed connective tissue disease (MCTD), polymyositis (PM)/ dermatomyositis (DM) and systemic lupus erythematosus (SLE) are chronic, rheumatic, systemic inflammatory disorders. The disorders depend on several factors of both genetic and environmental origin. LÄS MER

  7. 5. Molecular and clinical sexual dimorphism in systemic autoimmunity

    Författare :Jorge Iván Ramírez Sepúlveda; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Biological differences between the sexes of a species, also known as sexual dimorphism, can be found throughout developmental, physiological and pathological processes. In human disease, sexual dimorphism can explain marked differences in disease susceptibility. LÄS MER