Sökning: "Institutionen för immunteknologi"

Visar resultat 41 - 45 av 77 avhandlingar innehållade orden Institutionen för immunteknologi.

  1. 41. Transcriptional analysis of mantle cell lymphoma - a global search for cellular origin and therapeutic targets

    Författare :Sara Ek; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; oncology; cancerology; Cytologi; onkologi; Cytology; somatic mutation; microarray; tumour; mantle cell lymphoma; B cell;

    Sammanfattning : This thesis is based upon four original papers describing the characterisation of mantle cell lymphoma (MCL) tumours and cell lines in comparison with different populations of normal B cells. Gene expression profiling, which were used in the studies, has during recent years developed as an important tool in characterisation of different types of malignancies. LÄS MER

  3. 42. Proteomic analysis of Parkinson’s disease mechanism and biomarkers

    Författare :Dani Flinkman; Institutionen för immunteknologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  4. 43. GARD – Genomic Allergen Rapid Detection : From Biomarker Discovery towards a State-of-the-art Testing Platform for Chemical Sensitizers

    Författare :Andy Forreryd; Institutionen för immunteknologi; []
    Nyckelord :In vitro assay; skin sensitization; respiratory sensitization; predictive biomarker signatures; in vitro test; hudsensibilisering; luftvägssensibilisering; biomarkörsignaturer;

    Sammanfattning : Chemical hypersensitivity reactions induced in the skin or in the respiratory tract are important health concerns and develops following repeated exposure to certain chemicals, termed sensitizers. To prevent such hazardous compounds from entering the consumer market, legal frameworks within EU require chemicals to be tested for their capacity to induce hypersensitivity. LÄS MER

  5. 44. Expression of Ig genes. Regulation of transcription and production of human antibodies

    Författare :Christina Furebring; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Bioteknik; Biotechnology; human antibodies; immunoglobulin gene expression; 3 enhancer; serology; transplantation; Immunologi; serologi;

    Sammanfattning : During B lymphocyte development, the transcriptional activity of the IgH locus is subject to spatial and temporal changes. The 3' enhancer (3'E) has been suggested to play an important role in regulation of immunoglobulin gene expression late in B cell development. LÄS MER

  7. 45. Dissection of the tonsillar cancer immune microenvironment : Perspectives of the myeloid APC – T-cell axis

    Författare :David Gomez Jimenez; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dendritic cell; Macrophage; CD8 T-cell; Human papillomavirus HPV ; Tonsillar cancer; Tumor microenvironment; Immuno-oncology; Single-cell RNA sequencing; Spatial proteomics; Flow Cytometry;

    Sammanfattning : Tonsillar cancer (TC) is a subset of head and neck cancer (HNC). TC incidence is sharply rising due to an increased prevalence of human papillomavirus (HPV) infection in the western world. Currently HPV status is considered during clinical staging due to its positive association to patient prognosis. LÄS MER