Sökning: "skin sensitization"

Visar resultat 1 - 5 av 53 avhandlingar innehållade orden skin sensitization.

  1. 1. Allergenic Oxidation Products from Fragrance Terpenes. Chemical Analysis and Determination of Sensitizing Potency

    Författare :Johanna Rudbäck; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Autoxidation; Contact allergy; Essential oils; Fragrances; Hydroperoxides; Ionization techniques; Mass spectrometry; Prehapten; Sensitization; Skin; Structure-activity relationships; Terpenes;

    Sammanfattning : The ubiquitous presence of fragrance compounds in consumer products has resulted in a high frequency of contact allergy to fragrances in the population. For prevention purposes and according to EU regulations, cosmetics must be labeled when containing the most prominent fragrance allergens in concentrations exceeding 0. LÄS MER

  3. 2. Mechanistic Toxicology : Molecular interactions and underlying mechanisms of dendritic cell activation in skin sensitization

    Författare :Tim Lindberg; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skin Sensitization; Toxicology; Mechanisms; Dendritic Cells;

    Sammanfattning : Allergic skin diseases caused by low molecular weight chemical compounds are a major health concern among the general population, especially in certain occupational groups. To limit exposure to such compounds, it is important that thorough risk assessments are performed before products reach the consumer market. LÄS MER

  4. 3. GARD – Genomic Allergen Rapid Detection : From Biomarker Discovery towards a State-of-the-art Testing Platform for Chemical Sensitizers

    Författare :Andy Forreryd; Institutionen för immunteknologi; []
    Nyckelord :In vitro assay; skin sensitization; respiratory sensitization; predictive biomarker signatures; in vitro test; hudsensibilisering; luftvägssensibilisering; biomarkörsignaturer;

    Sammanfattning : Chemical hypersensitivity reactions induced in the skin or in the respiratory tract are important health concerns and develops following repeated exposure to certain chemicals, termed sensitizers. To prevent such hazardous compounds from entering the consumer market, legal frameworks within EU require chemicals to be tested for their capacity to induce hypersensitivity. LÄS MER

  5. 4. Cobalt in the hard metal production industry : exposure via inhalation and skin and the inflammatory response in human keratinocytes

    Författare :Maria Klasson; Eva Särndahl; Håkan Westberg; Magnus Lindberg; Alexander Persson; Kristina Jakobsson; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cobalt; cobalt chloride; skin; HaCaT; in vitro; cell viability; pro-inflammatory cytokines; NLRP3 inflammasome;

    Sammanfattning : Cobalt is a strong sensitizer and can cause contact allergy upon both direct contact or from airborne exposure on the skin. In the skin, keratinocytes are the first cells to come in contact with the metal and will react and respond to the danger by triggering an alarm system resulting in an inflammatory response in the skin. LÄS MER

  7. 5. Allergic sensitization among schoolchildren in northern Sweden : time trends, risk factors and relation to asthma, allergic rhinitis and lung function

    Författare :Joakim Bunne; Eva Rönmark; Linnea Hedman; Caroline Nilsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Allergy; Allergic sensitization; Aeroallergens; Allergic disease; Asthma; Rhinitis; Lung function; Epidemiology; Schoolchildren; Adolescence; Childhood; epidemiologi; Epidemiology; Public health; folkhälsa;

    Sammanfattning : Background: Asthma and allergic rhinitis are common chronic diseases of childhood.Their prevalence has increased globally in the 20th century, with regionally diverging trends in recent years. LÄS MER