Sökning: "Spatial proteomics"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden Spatial proteomics.

  1. 1. Neuropeptidomics – Expanding Proteomics Downwards

    Författare :Marcus Svensson; Per Andrén; Per Svenningsson; Jonathan Sweedler; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical pharmacology; proteomics; peptidomics; mass spectrometry; neuropeptide; chromatography; Farmaceutisk farmakologi; PHARMACY; FARMACI;

    Sammanfattning : Biological function is mainly carried out by a dynamic population of proteins which may be used as markers for disease diagnosis, prognosis, and as a guide for effective treatment. In analogy to genomics, the study of proteins is called proteomics and it is generally performed by two-dimensional gel electrophoresis and mass spectrometric methods. LÄS MER

  2. 2. Spatiotemporal characterization of the human proteome

    Författare :Diana Mahdessian; Emma Lundberg; Arne Lindqvist; KTH; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Spatial proteomics; Spatiotemporal proteomics; Immunofluorescence; Human Protein Atlas; Cell compartments; Single cell proteomics; Cell cycle; Cancer;

    Sammanfattning : Characterizing the molecular components of the basic unit of life; the cell, is crucial for a complete understanding of human biology. The cell is divided into compartments to create a suitable environment for the resident proteins to fulfill their functions. LÄS MER

  3. 3. On computational methods for spatial mapping of thehuman proteome

    Författare :Casper F. Winsnes; Emma Lundberg; Ida-Maria Sintorn; KTH; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Spatial proteomics; Human Protein Atlas; Micronuclei; Citizen science; Biotechnology; Bioteknologi;

    Sammanfattning : Proteins are complex molecules that are involved in almost every task in the body. In general, the role a protein fulfills is highly dependent on where in the cell it is located, its subcellular localization. LÄS MER

  4. 4. Steady, ready, go - proteomics of etioplast inner membranes reveals a high readiness for light

    Författare :Lisa A. Blomqvist; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :chloroplast; etioplast; NADPH:protochlorophyllide oxidoreductase; prolamellar body; proteomics; prothylakoid; transmembrane; Triticum aestivum; wheat;

    Sammanfattning : Light is essential for development of photosynthetically active chloroplasts. In the absence of light proplastids develop into etioplasts which are readily transformed into chloroplasts upon illuminat... LÄS MER

  5. 5. A Proteomic Dissection of Breast Cancer - Via Cells and Organelles to Pathways

    Författare :Linn Antberg; Institutionen för immunteknologi; []
    Nyckelord :Proteomics; Mass spectrometry; Breast cancer; DNA repair; Organelle fractionation; Tumour subpopulations;

    Sammanfattning : Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in females worldwide. Breast tumours are extremely heterogeneous, and each patient’s disease has different causes, prognosis and appropriate treatments associated with it. LÄS MER