Sökning: "Tonsillar cancer"

Visar resultat 1 - 5 av 27 avhandlingar innehållade orden Tonsillar cancer.

  1. 1. Immune cell phenotypes of head and neck lesions associated with viral infections

    Författare :Aastha Sobti; Institutionen för immunteknologi; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human papilloma virus HPV ; Epstein-Barr virus; tonsillar cancer; nasopharyngeal cancer; laryngeal papilloma; tumour microenvionment; Immune cells; flow cytometery; Spatial proteomics;

    Sammanfattning : Tonsillar cancer (TC) and nasopharyngeal cancer (NPC) are associated with high-risk humanpapillomavirus (HPV) and Epstein-Barr virus (EBV), respectively. Similarly, benign lesions, knownas laryngeal papilloma (LP), are associated with low-risk HPV. LÄS MER

  3. 2. Potential immunoregulatory role of T and dendritic cells in cancer : Investigations based on transcriptional analysis

    Författare :Milad Abolhalaj; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dendritic cells; T cells; head and neck cancer; acute myeloid leukemia; bladder cancer; T cell exhaustion;

    Sammanfattning : Cancer is a complex disease with various genetic and epigenetic driving factors. Cancer cells form a favored microenvironment to sustain their uncontrolled behavior leading to abnormal growth. With standard treatment including chemotherapy, relapse risk is high due to the resistance that cancer cells can develop against chemotherapy agents. LÄS MER

  4. 3. Human papillomavirus in tonsillar cancer

    Författare :Hanna Mellin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human papillomviruses (HPVs) are known to be causative agents for the development of cervical carcinoma. To what extent HPV is associated with head and neck cancer remains to be clarified, but an association to tonsillar cancer has been proposed. Importantly, the oncogenes of HPV-16, namely E6 and E7, are generally expressed in tonsillar cancer. LÄS MER

  5. 4. Studies on the occurrence and effects of human papillomavirus in tumors of the head and neck

    Författare :David Lindquist; Tina Dalianis; Sonia Andersson; Karolinska Institutet Institutionen för onkologi-patologi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; onkologi; Oncology;

    Sammanfattning : The presence of human papillomavirus (HPV) in squamous cell carcinoma of the head and neck (HNSCC) was first reported in 1985. Since then, this association has been studied intensively and today there is substantial evidence for HPV as a causative agent and positive prognostic factor for clinical outcome in tonsillar cancer, but the association to other HNSCC is still unclear. LÄS MER

  7. 5. Human papillomavirus in recurrent respiratory papillomatosis, tonsillar and mobile tongue cancer

    Författare :Christos Loizou; Katarina Olofsson; Karin Nylander; David Lindquist; Göran Laurell; Stina Syrjänen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human papillomavirus; recurrent respiratory papillomatosis tonsillar cancer; mobile tongue cancer; voice-; and quality of life; p16; syndecan-1; northern Sweden;

    Sammanfattning : This thesis focuses on the effects of the human papillomavirus (HPV) in tonsillar cancer, mobile tongue cancer, and recurrent respiratory papillomatosis (RRP). The purpose was to characterize patients with RRP in northern Sweden in order to identify more care-intensive RRP patients and to describe the voice and quality of life aspects that follow RRP. LÄS MER