Sökning: "Identical by Descent mapping"

Hittade 4 avhandlingar innehållade orden Identical by Descent mapping.

  1. 1. Topics in Human Gene Mapping

    Författare :Azra Kurbasic; Matematisk statistik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; actuarial mathematics; Statistik; programming; Statistics; Mathematics; Naturvetenskap; Natural science; hidden Markov model; linkage analysis; Human genome; disease gene; programmering; aktuariematematik; operationsanalys; operations research; Matematik;

    Sammanfattning : This thesis is interdisciplinary between Mathematical Statistics, Genetics, and Medicine. It mainly consists of topics in mathematical modelling of the correlation of inheritance of genes and disease in a family, a method called linkage analysis. It is organized as follows. LÄS MER

  3. 2. Genetic Analysis of Fat Metabolism in Domestic Pigs and their Wild Ancestor

    Författare :Frida Berg; Leif Andersson; Maria Moller; Stefan Marklund; Sigbjörn Lien; Uppsala universitet; []
    Nyckelord :Genetics; Pig; Quantitative Trait Locus; Fat deposition; FAT1; Linkage map; RH map; Comparative map; Backcross; Identical by Descent mapping; Brown adipose tissue; UCP1; Genetik;

    Sammanfattning : The domestication of the pig began about 9 000 years ago and many of the existing domestic breeds have been selected for phenotypic traits like lean meat and fast growth. Domestic pigs are phenotypically very different from the ancestral wild boar that has adapted to survive in their natural environment. LÄS MER

  4. 3. Molecular Genetic Studies of ALSG, Kostmann Syndrome and a Novel Chromosome 10 Inversion

    Författare :Miriam Entesarian; Niklas Dahl; Niels Tommerup; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical genetics; Klinisk genetik; Clinical Genetics; klinisk genetik;

    Sammanfattning : In summary, this thesis presents the localisation and identification of genetic variants of which some are disease associated and some considered to be neutral. Knowledge of the basic mechanisms behind human disorders is important both from a biological and medical point of view. LÄS MER

  5. 4. Genetics of pain : studies of migraine and pain insensitivity

    Författare :Anna Norberg; Monica Holmberg; Arn van den Maagdenberg; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Migraine; pain insensitivity; susceptibility genes; genome-wide scan; linkage; polymorphism; association; HSAN V; nerve growth factor; neurite outgrowth; Medical genetics; Medicinsk genetik;

    Sammanfattning : Pain is a major public health issue throughout the world. Increased understanding of the different forms of pain and identification of susceptibility genes could contribute to improved treatments. LÄS MER