Sökning: "I O ratio"

Visar resultat 1 - 5 av 69 avhandlingar innehållade orden I O ratio.

  1. 1. Model-Based Optimization of Clinical Trial Designs

    Författare :Camille Vong; Mats O. Karlsson; Andrew C. Hooker; Lena E. Friberg; Marylore Chenel; Oliver Sander; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nonlinear mixed-effects models; pharmacometrics; likelihood ratio test; NONMEM; power; sample size; study design; proof-of-concept; dose-finding; population optimal design; LOQ; BQL data; neutropenia; docetaxel; myelosuppression; thrombocytopenia; MTD; Bayesian methods; 3 3 algorithm; dose escalation study; Pharmaceutical Science; Farmaceutisk vetenskap;

    Sammanfattning : General attrition rates in drug development pipeline have been recognized as a necessity to shift gears towards new methodologies that allow earlier and correct decisions, and the optimal use of all information accrued throughout the process. The quantitative science of pharmacometrics using pharmacokinetic-pharmacodynamic models was identified as one of the strategies core to this renaissance. LÄS MER

  3. 2. Development of Concentrating Photovoltaic-Thermal Solar Collectors

    Författare :João Gomes; Björn O. Karlsson; Mats Rönnelid; Göran Lundgren; Heimo Zinko; Högskolan i Gävle; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Solar Energy; Photovoltaic-Thermal PVT ; Concentration; Collector Testing; Silicon Cell Encapsulation; Ray Tracing; Market Survey; String Layout; Prototype Collectors; Solenergi; Fotovoltaisk-termisk PVT ; Koncentration; Solfångarprovning; Inkapsling av kiselceller; Strålgångsberäkning; Marknadsundersökning; Strängdesign; Solfångarprototyper; Hållbar stadsutveckling; Sustainable Urban Development;

    Sammanfattning : Fossil fuels have greatly improved human living standards and saved countless lives. However, today, their continued use threatens human survival, as CO2 levels rise at an unprecedented pace to levels never seen during human existenceon earth. LÄS MER

  4. 3. Monopolar and Bipolar Membranes in Organic Bioelectronic Devices

    Författare :Erik O. Gabrielsson; Magnus Berggren; Edwin Jager; Daniel Simon; Ari Ivaska; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; bioelectronics; ionic; ion transport; bipolar membrane; conjugated polymer; amyloid; self-assembly;

    Sammanfattning : In the 1970s it was discovered that organic polymers, a class of materials otherwise best know as insulating plastics, could be made electronically conductive. As an alternative to silicon semiconductors, organic polymers offer many novel features, characteristics, and opportunities, such as producing electronics at low costs using printing techniques, using organic chemistry to tune optical and electronic properties, and mechanical flexibility. LÄS MER

  5. 4. Synthesis and characterization of two- and three-dimensional nanolaminated carbides

    Författare :Quanzheng Tao; Johanna Rosén; Per O A Persson; Amit Keren; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : This thesis is focused towards the synthesis and characterization of novel nanolaminated materials in primarily bulk (powder) form. Of particular interest is magnetic materials, or laminates that can be used as precursor for two-dimensional (2D) materials. LÄS MER

  7. 5. Growth and Characterization of ZnO Nanocrystals

    Författare :Leif KE Ericsson; Kjell O Magnusson; Lars SO Johansson; Hanmin M Zhang; Omer Nour; Karlstads universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; ZnO; Nanocrystals; Surface physics; XPS; SEM; AES; AFM; STM; Physics; Fysik;

    Sammanfattning : The understanding of surfaces of materials is of crucial importance to all of us. Considering nanocrystals (NCs), that have a large surface to bulk ratio, the surfaces become even more important. Therefore, it is important to understand the fundamental surface properties in order to use NCs efficiently in applications. LÄS MER