Sökning: "Host defense peptides"

Visar resultat 11 - 15 av 51 avhandlingar innehållade orden Host defense peptides.

  1. 11. Role of macrophage receptor MARCO in host defense

    Författare :Marko Sankala; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MARCO; innate immunity; scavenger receptor.;

    Sammanfattning : Innate immunity, the first line of defense against infectious microorganisms, appeared early in evolution. Innate immunity relies on specialized cells such as macrophages that are the first to encounter pathogens during infection. LÄS MER

  3. 12. Host Defense Properties of Collagen VI. A novel concept in connective tissue innate immunity

    Författare :Suado M Abdillahi; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Innate Immunity; Antimicrobial peptides; Collagen VI; Chronic obstructive pulmonary disease COPD ;

    Sammanfattning : Rapid and powerful host defense mechanisms are essential in order to overcome harmful actions of pathogenic bacteria. Antimicrobial peptides (AMPs) and proteins are vital effector molecules of the fast-acting innate immune system and exist virtually in all living organisms. LÄS MER

  4. 13. Antimicrobial peptides as defense molecules at the interface of the host and bacteria

    Författare :Ulf Meyer-Hoffert; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Microbes surround us. However, most of the time we are unaware of them. Our epithelial surfaces, which provide the physical barrier and separate us from the environment, are usually free of signs of a battle taking place. LÄS MER

  5. 14. Host-pathogen interactions between Francisella tularensis and Drosophila melanogaster

    Författare :Malin Vonkavaara; Svenja Stöven; Ingrid Faye; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; arthropod vector; JNK; lipopolysaccharide; antimicrobial peptides; Clinical Bacteriology; klinisk bakteriologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Francisella tularensis is a highly virulent Gram-negative bacterium causing the zoonotic disease tularemia. Arthropod-borne transmission plays an important role in transferring the disease to humans. F. LÄS MER

  7. 15. LL-37-derived cyclic antimicrobial drug leads : Design, synthesis, activity and different ways of creating them 

    Författare :Taj Muhammad; Ulf Göransson; Sunithi Gunasekera; Adam A. Strömstedt; Wang Guangshun; Uppsala universitet; []
    Nyckelord :antimicrobial peptide; host defense; antimicrobial; LL-37; KR-12; peptide cyclisation; peptide dimerisation; croos-linking; cyanobactin-macrocyclase; PatGmac; butelase 1; enzymatic cyclisation; immobilisation; Farmakognosi; Pharmacognosy;

    Sammanfattning : In an era where last-line antibiotics are failing, one of the powerful approaches to develop novel therapeutic agents is to turn back to nature in order to identify possible drug candidates. Among the potential candidates, antimicrobial peptides (AMPs) have garnered much attention as an antimicrobial. LÄS MER