Sökning: "High throughput sequencing"
Visar resultat 16 - 20 av 170 avhandlingar innehållade orden High throughput sequencing.
16. Advances in DNA Detection
Sammanfattning : DNA detection technologies have an increasing importance in our everyday lives, with applications ranging from microbial diagnostics to forensic analysis, food safety evaluation, and environmental monitoring. Currently, as the associated costs decrease, DNA diagnostic techniques are routinely used in research laboratories, in clinical and forensic practice. LÄS MER
17. Fungal molecular ecology in boreal forests and challenges associated with unidentified environmental DNA sequences
Sammanfattning : Many fungi are characteristically difficult to observe and collect, making the process of documenting the world’s fungal diversity challenging. The vast majority of fungal species are undescribed. LÄS MER
18. Phasing single DNA molecules with barcode linked sequencing
Sammanfattning : Elucidation of our genetic constituents has in the past decade predominately taken the form of short-read DNA sequencing. Revolutionary technology developments have enabled vast amounts of biological information to be obtained, but from a medical standpoint it has yet to live up to the promise of associating individual genotypes to phenotypic states of wide-spread clinical relevance. LÄS MER
19. Exploring genetic heterogeneity in cancer using high-throughput DNA and RNA sequencing
Sammanfattning : High-throughput sequencing (HTS) technology has revolutionised the biomedical sciences, where it is used to analyse the genetic makeup and gene expression patterns of both primary patient tissue samples and models cultivated in vitro. This makes it especially useful for research on cancer, a disease that is characterised by its deadliness and genetic heterogeneity. LÄS MER
20. Exploring the interplay between mRNA degradation and ribosome dynamics using high-throughput sequencing
Sammanfattning : Regulation of gene expression in response to fluctuating environments is essential for cellular survival. This regulation is multi-faceted, with mRNA abundance determined by both synthesis and decay. mRNA decay regulates transcript abundance, enabling swift transcriptomic adaptations. LÄS MER