Sökning: "bioconductor"

Hittade 2 avhandlingar innehållade ordet bioconductor.

1. 1. Exploring genetic heterogeneity in cancer using high-throughput DNA and RNA sequencing

   Författare :Erik Fasterius; Cristina Al-Khalili Szigyarto; Mathias Uhlén; Peter-Bram ’t Hoen; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Biotechnology; bioinformatics; RNA-seq; WGS; WES; systems biology; variant analysis; single nucleotide variant; gene expression; machine learning; clustering; open source; R; bioconductor; Python; Bioteknologi; Biotechnology;

   Sammanfattning : High-throughput sequencing (HTS) technology has revolutionised the biomedical sciences, where it is used to analyse the genetic makeup and gene expression patterns of both primary patient tissue samples and models cultivated in vitro. This makes it especially useful for research on cancer, a disease that is characterised by its deadliness and genetic heterogeneity. LÄS MER

3. 2. Functional analysis of genetic risk markers

   Författare :Jesper Robert Gådin; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Regulatory variants are the main factors responsible for genetic predisposition to how e.g. humans react differently to the environment. LÄS MER