Sökning: "Fetal stem cells"

Visar resultat 1 - 5 av 94 avhandlingar innehållade orden Fetal stem cells.

  1. 1. Neurogenesis from Neural Stem Cells, Ependymal Cells and Fibroblasts

    Författare :Karthikeyan Devaraju; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adult neurogenesis; stroke; neural stem cells; Lnk; ependymal cells; FoxJ1; cortical reprogramming;

    Sammanfattning : Stroke is a major cause of death and disability around the world. Stroke leads to loss of neurons and also other cells in the brain due to lack of blood supply. Currently no therapies are available to treat stroke-related disability. It has been shown that stroke leads to increased neurogenesis, birth of new neurons, within the brain. LÄS MER

  3. 2. Genetic Sex Differences in Early Human Neuronal Development : An Investigation in Embryo Tissue and Embryonic Stem Cells

    Författare :Philipp Pottmeier; Elena Jazin; Armin Raznahan; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sex chromosome; gametolog; x y homolog; male; female; sex differences; sex bias; embryonic stem cells; neurodevelopment; neuronal differentiation; neural stem cells; genetics; neurodevelopmental disorders; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi; Neuroscience; Neurovetenskap; Medicinsk genetik; Medical Genetics;

    Sammanfattning : Sex differences in the human body affect many different organs and tissues, some of them have an effect on the human brain and its development. In the developing nervous system, sex differences can bias the number or functionality of neurons, glial cells or synapses. As a result, neural networks might develop with a sex-specific bias. LÄS MER

  4. 3. Characterisation of human fetal mesenchymal stem cells

    Författare :Cecilia Götherström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Mesenchymal stem cells; fetal stem cell transplantation; intrauterine transplantation; osteogenesis imperfecta; mixed lymphocyte culture; gene array;

    Sammanfattning : Mesenchymal stem cells (MSCs) are present in various tissues of fetal and adult origin. I isolated and expanded MSCs from human fetal 1st trimester livers and observed that they have a shorter cell doubling time compared to adult bone marrow-derived MSCs. LÄS MER

  5. 4. Cellular pathways and molecular regulation of hematopoietic stem cells

    Författare :Kristina Anderson; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; β-catenin.; lineage commitment; hematopoietic stem cells; lineage priming; Wnt signaling pathway; biphenotypic cells; PAX5;

    Sammanfattning : Hematopoietic stem cells (HSCs) are defined by their unique properties to self-renew and differentiate into all hematopoietic cell lineages. Residing in the bone marrow (BM), adult HSCs are organized in a hierarchy of cells that differ in their self-renewal and proliferative capacity. LÄS MER

  7. 5. Switching ON Fetal B Lymphopoiesis

    Författare :Trine Kristiansen; Avdelningen för molekylär hematologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B-1 B cells; Lin28; Fetal hematopoietic stem cells;

    Sammanfattning : B-1a cells are innate-like lymphocytes that develop primarily during fetal and neonatal life, whereas adult bone marrow (BM) hematopoietic stem cells (HSCs) preferentially give rise to follicular B-2 cells. Functioning at the interface of the innate and adaptive immune systems, B-1a cells provide a non-redundant first line of defense prior to the temporally delayed establishment of a B-2 cell response. LÄS MER