Sökning: "cortical reprogramming"
Hittade 4 avhandlingar innehållade orden cortical reprogramming.
1. Generation of cortical neurons through reprogramming technology
Sammanfattning : The human cortex is affected by several debilitating acute and chronic neurodegenerative disorders such as stroke, traumatic brain injury, amyotrophic lateral sclerosis and Alzheimer’s disease, which target specific types of cortical neurons. Emerging evidence indicates that stem cells and reprogrammed cells can be used to generate human cortical neurons both for cell replacement by transplantation, and for disease modeling and drug screening. LÄS MER
2. Neurogenesis from Neural Stem Cells, Ependymal Cells and Fibroblasts
Sammanfattning : Stroke is a major cause of death and disability around the world. Stroke leads to loss of neurons and also other cells in the brain due to lack of blood supply. Currently no therapies are available to treat stroke-related disability. It has been shown that stroke leads to increased neurogenesis, birth of new neurons, within the brain. LÄS MER
3. Neural Stem Cells - interaction with the brain and prospects for cell replacement therapy for Stroke
Sammanfattning : Stroke is an acute neurological condition and the leading cause of disability in adult humans. Treatments for efficient recovery are not available. The most common form of stroke results from the occlusion of the middle cerebral artery, which causes loss of brain parenchyma and many types of neurons as well as astrocytes and oligodendrocytes. LÄS MER
4. Alterations in proliferation and differentiation of neural stem cells induced by adverse neurodevelopmental factors
Sammanfattning : Predisposition to diseases can be acquired during early stages of development and resolve into an actual disorder later in life. Early life programming defines the association between challenges during pregnancy that result in altered fetal growth, and developmental and adult disorders. LÄS MER