Avancerad sökning

Hittade 4 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Calciumhomeostasis and Vitamin D in Obesity and Preeclampsia

    Författare :Hella Hultin; Per Hellman; Ylva Pernow; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Calcium homeostasis; vitamin D; preeclampsia; obesity; parathyroid hormone; Endocrine surgery; Endokrin kirurgi; Kirurgi; Surgery;

    Sammanfattning : Normal physiological functioning is highly dependent of calcium and the concentration range is very narrow. Normal calcium levels are so crucial to survival that the body will de-mineralize bone if the levels are insufficient. A prerequisite for normal calcium uptake is a normal Vitamin D level. LÄS MER

  3. 2. Modern Staging in Primary Breast Cancer-aspects of micrometastatic disease in bone marrow and molecular profiles in lymph node metastases

    Författare :Anna-Karin Falck; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; biomarker expression; lymph node metastases; relapse; molecular subtype classification; disseminated tumour cells; bone marrow; prognosis; mode of detection;

    Sammanfattning : Breast cancer is a heterogeneous disease with variations in the biological profile and subsequent clinical prognosis. Molecular mechanisms for tumour progression are currently being explored in scientific settings, suggesting parallel evolution of tumour cells at primary and metastatic locations. LÄS MER

  4. 3. The Prognostic and Treatment Predictive Value of Proliferation and TIMP-1 in Breast Cancer

    Författare :Marie Klintman; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; predictive marker; resistance; prognostic factor; proliferation; prospective; TIMP-1; Ki67; S-phase; MAI; PPH3; cyclin B1; cyclin A; node-negative; validation;

    Sammanfattning : Breast cancer is the most common tumour form and the second leading cause of death in solid tumours in women in the Western world. Despite improvements in the treatment, a considerable number of patients will relapse and die from their breast cancer. LÄS MER

  5. 4. Molecular Characterization of Male Breast Cancer

    Författare :Ida Johansson; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; male breast cancer; aCGH; gene expression; DNA-methylation; microarray; profiling; NAT1; THY1;

    Sammanfattning : Cancer is today a major healthcare problem worldwide. There are many forms of cancer, which is a genetic disease, believed to result from a multistep process with genetic and epigenetic changes accumulating over time. Breast cancer is one of the most common forms of cancer in women, while it is much more rare in men. LÄS MER