Sökning: "Conjugation length"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden Conjugation length.

1. 1. Fluorescent thiophene-based ligands for detection and characterization of disease-associated protein aggregates

   Författare :Therése Klingstedt; Peter Nilsson; Per Hammarström; Henrik Zetterberg; Linköpings universitet; []
   Nyckelord :;

   Sammanfattning : In this thesis the unique optical properties of fluorescent ligands termed luminescent conjugated oligothiophenes (LCOs) have been used to study a variety of protein aggregates associated with human protein misfolding disease. This heterogeneous group of diseases contains well known and fatal members such as Alzheimer´s and Huntington´s disease and the development of sensitive tools for the detection and characterization of protein aggregates is crucial for unravelling the complexity of these pathologies. LÄS MER

3. 2. Synthesis of Orthogonally Functionalized Oligosaccharides for Self-assembled Monolayers and as Multimodal Tools in Chemical Biology

   Författare :Timmy Fyrner; Peter Konradsson; Stefan Svensson; Bo Liedberg; Ulf Ellervik; Linköpings universitet; []
   Nyckelord :Oligosaccharide synthesis; glycosylation; thioglycosides; orthogonally protected; oligo lactosides ; spacer molecule; heterobifunctional; surface plasmon resonance; lipid anchor; self-assembled monolayers; glyconanoparticles;

   Sammanfattning : This thesis covers different topics in the field of synthetic organic chemistry combined with the field of surface science and glycobiology.First, the text presents a series of orthogonally protected oligosaccharides (tri-, penta-, and heptasaccharides) of varying length and structures, which are synthesized with the aim of developing novel heterobifunctional biocompatible cross-linkers. LÄS MER

4. 3. Electronic and Vibrational Coherence in Photosynthetic and Model Systems

   Författare :Mirianas Chachisvilis; Kemisk fysik; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Kemi; Chemistry; Ultrafast relaxation; Porphyrins; Delocalization; Anisotropy; Wavepacket; Vibrational Coherence; Excitons; Electronic coherence; Energy transfer; Femtosecond spectroscopy; Photosynthesis;

   Sammanfattning : Ultrafast optical response and excitation energy dynamics in light harvesting pigment-protein complexes and in a few model systems have been studied both experimentally and theoretically. Femtosecond light pulses were employed to excite the system and monitor the subsequent time evolution of the transient absorption kinetics and anisotropy. LÄS MER

5. 4. Digital holographic reconstructions of ultrasound from laser vibrometry recordings

   Författare :Erik Olsson; Luleå tekniska universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Experimental Mechanics; Experimentell mekanik;

   Sammanfattning : If sound and noise from an engine, say a lawn mower, is to be reduced, it is of advantage to know from which part of the machine the noise is coming. An interesting medical application for localization of sound sources is optoacoustic imaging of tissue. LÄS MER

7. 5. Characterization of Fluorescent Dyes for Biochemical Applications. Chemometric Analysis of Spectroscopic Data

   Författare :Jan Nygren; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; principal component analysis; fluorescein; chemometrics; optical spectroscopy; fluorophores; thiazole orange;

   Sammanfattning : Fluorescent dyes are used in a number of different biochemical applications to visualize and probe biomolecules. The aim of this work was to characterize the spectroscopic properties of two such dyes, fluorescein and thiazole orange, and to develop chemometric methods to extract further information from these data. LÄS MER