Sökning: "Therése Klingstedt"

Hittade 1 avhandling innehållade orden Therése Klingstedt.

1. 1. Fluorescent thiophene-based ligands for detection and characterization of disease-associated protein aggregates

   Författare :Therése Klingstedt; Peter Nilsson; Per Hammarström; Henrik Zetterberg; Linköpings universitet; []
   Nyckelord :;

   Sammanfattning : In this thesis the unique optical properties of fluorescent ligands termed luminescent conjugated oligothiophenes (LCOs) have been used to study a variety of protein aggregates associated with human protein misfolding disease. This heterogeneous group of diseases contains well known and fatal members such as Alzheimer´s and Huntington´s disease and the development of sensitive tools for the detection and characterization of protein aggregates is crucial for unravelling the complexity of these pathologies. LÄS MER