Sökning: "Henrik Zetterberg"

Hittade 4 avhandlingar innehållade orden Henrik Zetterberg.

  1. 1. Transcriptional regulation of the Epstein-Barr virus nuclear antigen 1 gene in latent and lytic stages of infection

    Författare :Henrik Zetterberg; Göteborgs universitet; []
    Nyckelord :Epstein-Barr virus; EBNA1; Burkitt s lymphoma; nasopharyngeal carcinoma; ; B-lymphocyte; transformation; transcriptional regulation;

    Sammanfattning : Epstein-Barr virus (EBV) is a lymphotropic herpesvirus that infects more than 90% of humans worldwide. The virus is the causative agent of infectious mononucleosis, a self-limiting lymphoproliferative disorder, and is also associated with a variety of malignancies including Burkitt's lymphoma (BL), Hodgkin's disease (HD), nasopharyngeal carcinoma (NPC), and lymphoproliferative disorders in immunocompromised individuals. LÄS MER

  3. 2. Good Ecological Status : Advancing the Ecology of Law

    Författare :Henrik Josefsson; Charlotta Zetterberg; Gabriel Michanek; Lena Gipperth; Uppsala universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; EU Water Framework Directive; Environmental Regulations.; Miljörätt; Environmental Law;

    Sammanfattning : For a meaningful discussion of the effectiveness of ecological objectives and ecological quality standards, their terms and purposes must be examined and clarified. This study explores the terms and content of ecological quality objectives and ecological quality standards, based on the Water Framework Directive’s legal conceptualization of ‘ecological status’. LÄS MER

  4. 3. Genetic variation in the folate receptor-alpha and methylenetetrahydrofolate reductase genes as determinants of plasma homocysteine concentrations

    Författare :Anna Böttiger; Torbjörn Nilsson; Henrik Zetterberg; Örebro universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Folate receptor-alpha; Folate; FOLR1; Haplotypes; Homocysteine; Methylenetetrahydrofolate reductase; MTHFR; Polymorphisms; Pyrosequencing®; SSCP; Medicine; Medicin; Biomedicin; Biomedicine;

    Sammanfattning : Elevated total plasma homocysteine (tHcy) is a risk factor for cardiovascular disease and neurocognitive disease such as dementia. The B vitamins folate and B12 are the main de terminants of tHcy. tHcy concentration can also be affected by mutations in genes coding for receptors, enzymes and transporters important in the metabolism of Hcy. LÄS MER

  5. 4. Fluorescent thiophene-based ligands for detection and characterization of disease-associated protein aggregates

    Författare :Therése Klingstedt; Peter Nilsson; Per Hammarström; Henrik Zetterberg; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : In this thesis the unique optical properties of fluorescent ligands termed luminescent conjugated oligothiophenes (LCOs) have been used to study a variety of protein aggregates associated with human protein misfolding disease. This heterogeneous group of diseases contains well known and fatal members such as Alzheimer´s and Huntington´s disease and the development of sensitive tools for the detection and characterization of protein aggregates is crucial for unravelling the complexity of these pathologies. LÄS MER