Sökning: "Cellular reprogramming"
Visar resultat 16 - 20 av 38 avhandlingar innehållade orden Cellular reprogramming.
16. Implementing new genomic tools to study ventral midbrain development and injury response in the newt Pleurodeles waltl
Sammanfattning : Mammals have a poor ability to regenerate organs or tissues. In particular, brain neurons do not regenerate after damage. A good example of this limitation is the irreversible degeneration of midbrain dopaminergic neurons in Parkinson’s disease (PD). Several strategies are being developed to treat PD. LÄS MER
17. The origin of symmetry in the metabolism of cancer – From systems biology to translational medicine
Sammanfattning : Why do not we have a cure for cancer yet? Cancer is the malady of the century, the most intensely studied disease of all time. The question is puzzling. It assumes that cancer is a single entity that we can target and eradicate. LÄS MER
18. Microfluidic Compartmentalization for Smart Materials, Medical Diagnostics and Cell Therapy
Sammanfattning : The organisation of fluids in small compartments is ubiquitous in nature, such as in the cellular composition of all life. This work explores several engineering avenues where microscale fluid compartmentalization can bring novel material properties or novel functionality in life sciences or medicine. LÄS MER
19. Polar Growth in Streptomyces venezuelae
Sammanfattning : Cell polarity is an ubiquitous and important phenomenon relevant for a plethora of cellular functions. One type of cell polarity is polar growth, where an organism only synthesizes cell envelope at designated locations in the cell. This requires highly organized localization of cellular activities. LÄS MER
20. Macromolecular Matchmaking : Mechanisms and Biology of Bacterial Small RNAs
Sammanfattning : Cells sense the properties of the surrounding environment and convert this information into changes in gene expression. Bacteria are, in contrast to many multi-cellular eukaryotes, remarkable in their ability to cope with rapid environmental changes and to endure harsh and extreme milieus. LÄS MER