Sökning: "cellterapi"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet cellterapi.

  1. 1. Microfluidic Compartmentalization for Smart Materials, Medical Diagnostics and Cell Therapy

    Författare :Emre Iseri; Wouter van der Wijngaart; Nicole Pamme; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Microfluidics; microfabrication; compartmentalization; partitioning; droplet microfluidics; self-assembly; 3D microarrays; soft composites; beads; particles; core-shell particle; point-of-care; diagnostics; dipstick; digital bioassays; lab-on-a-chip; urinary tract infection; bacteria detection; E. coli; cell encapsulation; hydrogel; cell therapy; spider silk; magnetic metamaterials.; Mikrofluidik; mikrotillverkning; kompartmentalisering; partitionering; droppmikrofluidik; självmontering; 3D-mikromatriser; mjuka kompositer; pärlor; partiklar; kärna-skalpartikel; vårdpunkt; diagnostik; mätsticka; digitala bioanalyser; laboration-a-chip; urinvägsinfektion; bakteriedetektering; E. coli; cellinkapsling; hydrogel; cellterapi; spindelsilke; magnetiska metamaterial.;

    Sammanfattning : The organisation of fluids in small compartments is ubiquitous in nature, such as in the cellular composition of all life. This work explores several engineering avenues where microscale fluid compartmentalization can bring novel material properties or novel functionality in life sciences or medicine. LÄS MER

  3. 2. Magnetic bead-based isolation of biological therapeutic modalities

    Författare :Nils A. Brechmann; Véronique Chotteau; Nigel Titchener-Hooker; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Magnetic bead separation; Magnetic beads; Protein A; Protein G; Negative cell isolation; Monoclonal antibody; induced pluripotent stem cells; human mesenchymal stem cells; Allogenic cell therapy; Biomanufacturing; cell clarification; Biotechnology; Bioteknologi;

    Sammanfattning : Biopharmaceutical modalities, such as monoclonal antibodies or the less established cell therapies, are nowadays very important for the treatment of severe or incurable diseases. The manufacturing of such modalities is complex and costly, including the downstream processing, which is highly essential to ensure the safety and quality of the product. LÄS MER

  4. 3. Generation of induced neurons via direct conversion in vivo and in vitro

    Författare :Olof Torper; Neurobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cellular reprogramming; cell replacement therapies; induced dopaminergic neurons; in vivo reprogramming; Lentiviral vectors; AAV vectors;

    Sammanfattning : Cellular reprogramming is when one cell is changed into another. This involves structural modifications on the DNA of a cell resulting in a transcriptional change. This occurs naturally during development when early pluripotent cells gradually differentiate into more specialized cells that finally result in a complete organism. LÄS MER

  5. 4. Gene therapy in a new model of delayed wound healing

    Författare :Patrik Velander; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IGF-1; Gene therapy; Diabetes; Animal model; EGF;

    Sammanfattning : Diabetes wounds result in significant morbidity, prolonged hospitalization and huge health care expenses. As of yet, no optimal animal models of diabetic wound healing exist to study potential beneficial therapies. Porcine wound healing is very similar to human wound healing. LÄS MER

  7. 5. Stem Cell Plasticity Controlling Neuronal Differentiation Prior to Cell Transplantation

    Författare :Laurent Roybon; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Differentiation; Stem cells; Immunology; serology; Immunologi; serologi; transplantation;

    Sammanfattning : Parkinson's disease (PD) is the second most common neurodegenerative disease and affects 2% of the population over 65 years of age. The disease is characterized by the progressive loss of dopaminergic neurons. Over time, symptoms increase and, in particular, lead to a dramatic slowness of movements. LÄS MER