Sökning: "Biologic treatments"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Biologic treatments.

  1. 1. Psoriasis in Sweden : observational studies from an epidemiological perspective

    Författare :David Hägg; Marcus Schmitt-Egenolf; Anders Sundström; Marie Eriksson; Bernt Lindelöf; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psoriasis; Systemic treatments; Biologic treatments; PASI; DLQI; Register-based research; Dermatology and Venerology; dermatologi och venereologi;

    Sammanfattning : Background: Psoriasis is a heterogeneous disease with several clinical manifestations; the symptoms are characterized by redness, scaliness and thickness of the skin. There are several treatment options available for psoriasis and patients with moderate to severe psoriasis generally need systemic agents. LÄS MER

  3. 2. Effectiveness and costs of new medical technologies : register-based research in psoriasis

    Författare :Jenny Norlin; Marcus Schmitt-Egenolf; Ulf Persson; Katarina Steen Carlsson; Lars-Åke Levin; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psoriasis; registers; EQ-5D; DLQI; PASI; biologics;

    Sammanfattning : Psoriasis is a chronic, immunological and systemic disease with an estimated prevalence of about 2-3 percent. Psoriasis is associated with the joint disease psoriasis arthropathy. There are several treatments options available for psoriasis and patients with moderate to severe psoriasis generally need systemic agents. LÄS MER

  4. 3. Pharmacometric Modeling in Rheumatoid Arthritis

    Författare :Brigitte Lacroix; Lena Friberg; Mats Karlsson; Maria Laura Sargentini-Maier; Kosmas Kretsos; Ekaterina Gibiansky; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatoid arthritis; PKPD; immunogenicity; ACR; IPPSE; certolizumab pegol;

    Sammanfattning : Biologic therapies have revolutionized the treatment of rheumatoid arthritis, a common chronic inflammatory disease, mainly characterized by the chronic inflammation of the joints. The activity and progression of the disease are highly variable, both between subjects and between the successive assessments for the same subject. LÄS MER

  5. 4. Radioiodine Therapy of Hyperthyroidism - Simplified patient-specific absorbed dose planning

    Författare :Helene Jönsson; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiobiologi; Radiofarmaceutisk teknik; Radiopharmaceutical technology; absorbed dose. optimise; hyperthyroidism; therapy; 131-I; radioiodine; Nukleärmedicin; radiobiology; Nuclear medicine;

    Sammanfattning : Radioiodine therapy of hyperthyroidism is the most frequently performed radiopharmaceutical therapy. To calculate the activity of 131-I to be administered for giving a certain absorbed dose to the thyroid, the mass of the thyroid and the individual biokinetic data, normally in the form of uptake and biologic half-time, have to be determined. LÄS MER

  7. 5. Biologics in Staphylococcus aureus arthritis

    Författare :Abukar Ali; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Staphylococcus aureus; CTLA4-Ig; IL-1 Ra; anti-TNF therapy; mouse; septic arthritis;

    Sammanfattning : The emergence of new type of drugs known as biologics has led to rapid disease improvements in many autoimmune arthritic patients. Nevertheless, most of these biologics are immunomodulators that may consequently increase the susceptibility of patients towards infections, such as septic arthritis. LÄS MER