Sökning: "Biochemical markers"

Visar resultat 16 - 20 av 186 avhandlingar innehållade orden Biochemical markers.

1. 16. Long-term treatment response, predictors and biochemical markers in Alzheimer’s disease

   Författare :Åsa Wallin; Klinisk minnesforskning; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; treatment response; cholinesterase inhibitor; CSF-biomarkers; pre-treatment progression; predictors; Alzheimer’s disease;

   Sammanfattning : Alzheimer’s disease (AD) is clinically characterised by an insidious onset with progressive symptoms of memory impairment, dysphasia, dyspraxia, dygnosia and visuospatial difficulties. Degeneration of neurons in specific regions of the brain, formation of senile plaques and neurofibrillary changes are some of the neuropathological features of the disease. LÄS MER

3. 17. Biochemical markers in dementia - Exploring Swedish registry data and the human proteome

   Författare :Tobias Skillbäck; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomarkers; Dementia; Alzheimer s disease; Vascular dementia; Creutzfeldt Jakob disease; Lewy body dementia; Frontotemporal dementia; Parkinson s disease dementia;

   Sammanfattning : Cerebrospinal fluid (CSF) biomarkers of neurodegenerative diseases have a wide scope of applications in diagnostics, prognosis assessment, disease staging, treatment evaluation and more. In this PhD project we aimed to expand the understanding of the properties of known CSF biomarkers of Alzheimer’s disease (AD) and other neurodegenerative diseases, including the most prevalent dementia disorders. LÄS MER

4. 18. Bone turnover markers and prediction of bone loss in elderly women

   Författare :Janaka Lenora; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bone turnover markers; DXA; elderly; osteoporosis; scintigraphy; Bone mineral density; quantitative ultrasound of the calcaneus; bone loss;

   Sammanfattning : Around 70,000 osteoporosis-related fractures occur in Sweden annually and approximately half of the women in western world will sustain a fragility fracture after the age of 50 years. Fracture preventive efforts require the identification of individuals who are at high risk. LÄS MER

5. 19. Clinical probability assessment and biochemical markers in the diagnosis of deep vein thrombosis

   Författare :Johan Elf; Malmö Klinisk koagulationsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Venous thrombosis; APC-PCI complex.; D-Dimer; Clinical probability; Diagnosis;

   Sammanfattning : The combination of pre-test clinical probability assessment and D-dimer test is now widely applied in the diagnostic process of DVT. The general objective of the present investigation was to validate these results in a Swedish routine emergency setting were the prevalence of the disease is high and were the clinical probability assessment was handled by many junior physicians. LÄS MER

7. 20. Unrecognized myocardial infarction and cardiac biochemical markers in patients with stable coronary artery disease

   Författare :Anna Nordenskjöld; Bertil Lindahl; Ole Fröbert; Kai Eggers; Torbjørn Omland; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Unrecognized myocardial infarction; Coronary artery disease; Prevalence; Prognosis; Troponin; NT-proBNP; Galectin-3; Medicin; Medicine;

   Sammanfattning : Aim: The overarching aim of the thesis was to explore the occurrence and clinical importance of two manifestations of myocardial injury; unrecognized myocardial injury (UMI) and altered levels of cardiac biochemical markers in patients with stable coronary artery disease (CAD).Methods: A prospective multicenter cohort study investigated the prevalence, localization, size, and prognostic implication of UMI in 235 patients with stable CAD. LÄS MER