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Visar resultat 1 - 5 av 24 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Angiopoietin-like protein 4 : an unfolding chaperone regulating lipoprotein lipase activity

    Författare :Valentina Sukonina; Gunilla Olivecrona; Lena Kjellen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipoprotein lipase; angiopoietin-like protein 4; protein folding; human adipose tissue; macrophages; peroxisome proliferator-activated receptor delta PPARδ ; Medical microbiology; Medicinsk mikrobiologi;

    Sammanfattning : Lipoprotein lipase (LPL) is the main enzyme hydrolyzing triglyceride-rich lipoproteins in plasma. Proteoglycan-bound LPL on the vascular endothelium represent the functional pool of active enzyme. LPL is regulated in a tissue specific manner according to metabolic demands. LÄS MER

  3. 2. Modulaton of gene expression in human aortic smooth muscle cells by Porphyromonas gingivalis : a possible association between periodontitis and atherosclerosis

    Författare :Boxi Zhang; Torbjörn Bengtsson; Allan Sirsjö; Hazem Khalaf; Julia Davies; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microarray; Angiopoietin; Smooth muscle cells; TNF; Periodontitis; Atherosclerosis; Porphyromonas gingivalis; Cancer; Inflammasome; Biomedicin; Biomedicine;

    Sammanfattning : Porphyromonas gingivalis is a gram-negative, rod-shaped, and anaerobic bacterium that is involved in the pathogenesis of periodontitis. P. gingivalis produces a variety of virulence factors including gingipains and fimbriae. LÄS MER

  4. 3. Pre-eclampsia – Possible to Predict? : A Biochemical and Epidemiological Study of Pre-eclampsia

    Författare :Marie Bolin; Helena Åkerud; Anna-Karin Wikström; Inger Sundström-Poromaa; Karel Marsal; Uppsala universitet; []
    Nyckelord :pre-eclampsia; angiopoietin; histidine-rich glycoprotein; hyperemesis gravidarum; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : Pre-eclampsia is a major cause of maternal and perinatal morbidity and mortality worldwide. A predictor of pre-eclampsia would enable intervention, close surveillance and timely delivery, and thereby reduce the negative consequences of the disorder. LÄS MER

  5. 4. Biomolecule Functionalization of Diamond Surfaces for Implant Applications - A Theoretical Study

    Författare :Yuan Tian; Karin Larsson; Lars Ojamäe; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Diamond; Biomolecules; Functionalization; VEGF; BMP2; Fibronectin; Chitosan; Heparin; RGD peptide; Angiopoietin; Theoretical; Kemi med inriktning mot materialkemi; Chemistry with specialization in Materials Chemistry;

    Sammanfattning : Diamond is a promising material with unique chemical properties. In this thesis, nano-scale diamond quantum size effects were investigated using several chemical property indicators. LÄS MER

  7. 5. The role of angiopoietin-like 4 in inflammation

    Författare :Terri Phua; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Inflammation is a homeostatically fundamental feature of the host defence surveillance system made up of an army of sentinel cells that guard against foreign intrusion. At the onslaught of an attack, primary immune responders (macrophages and neutrophils) secrete a plethora of cytokines and chemokines that attract secondary responders (T and B cells) to the site of inflammation, to eliminate the intrusion and encourage tissue healing. LÄS MER