Sökning: "Affinity chromatography"

Visar resultat 26 - 30 av 128 avhandlingar innehållade orden Affinity chromatography.

  1. 26. Composite Cryogels: Stationary Phase for Separation of Complex Media

    Författare :Solmaz Hajizadeh; Bioteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Composite cryogel; Complex media; Purification; Chromatography; Environmental application; Molecularly imprinted polymer;

    Sammanfattning : Demands for efficient, economical and fast separation and purification methods for various target molecules have led to the development of new techniques and materials for bioseparation processes. Separation can be carried out in both batch and chromatographic modes. LÄS MER

  2. 27. Rational and combinatorial protein engineering for vaccine delivery and drug targeting

    Författare :Maria Wikman; Stefan Ståhl; Carl A. K. Borrebaeck; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicine; affibody; affinity chromatography; biotin; combinatorial; delivery; phage display; Biomedicin; Microbiology; Mikrobiologi;

    Sammanfattning : This thesis describes recombinant proteins that have been generated by rational and combinatorial protein engineering strategies for use in subunit vaccine delivery and tumor targeting.In a first series of studies, recombinant methods for incorporating immunogens into an adjuvant formulation, e.g. LÄS MER

  3. 28. Studies on the Differential Specificity of Protein Kinases and Its Applications

    Författare :Mart Loog; Bengt Jergil; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Protein kinases; protein kinase inhibitors; substrate specificity; peptide libraries; affinity chromatography; Biokemi; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : Protein kinases are enzymes that catalyse the phosphoryl transfer from the g-phosphate of ATP to acceptor amino acids in proteins. The specificity of selected model protein kinases was studied at three different levels using a) novel bi-substrate-analogue inhibitors, b) synthetic peptide substrates and c) mutated protein substrate analogues. LÄS MER

  4. 29. The role of Moraxella catarrhalis outer membrane proteins in pathogenesis

    Författare :Taras Manolov; Malmö Klinisk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cathepsin G; inflammation; serum resistance; C3; complement; Moraxella catarrhalis; antichymotrypsin; affinity chromatography; purification;

    Sammanfattning : Moraxella catarrhalis is an important respiratory pathogen. It is a common cause of otitis media in children, a usual infections agent in sinusitis and makes up to 10% of all exacerbations of chronic obstructive pulmonary disease (COPD). LÄS MER

  5. 30. Antibody-Fragments: Protein Engineering, Process Development, and their Application as Affinity Ligands

    Författare :Laila Sakhnini; Tillämpad biokemi; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Monoclonal Antibodies; Aggregation; Biophysical Characterisation; Process Development; Affinity Adsorbents; Monoclonal Antibodies; Aggregation; Biophysical Characterisation; Process Development; Affinity Adsorbents;

    Sammanfattning : Monoclonal antibody (mAb) fragments have become the formats of choice for both biopharmaceuticals and ligands in analytical and preparative applications. Their smaller size enables additional advantages over full-length mAbs, such as improved tissue penetration, faster blood clearance for diagnostic applications, improved capacity, and enablement of multivalent formatting. LÄS MER