Sökning: "serum resistance"

Visar resultat 1 - 5 av 199 avhandlingar innehållade orden serum resistance.

  1. 1. Fat cell insulin resistance an experimental study focusing on molecular mechanisms in type 2 diabetes

    Detta är en avhandling från Umeå : Folkhälsa och klinisk medicin

    Författare :Frida Renström; Jan Eriksson; Anna Krook; [2007]
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; adipocyte; insulin signaling; insulin; glucose; IRS-1; glucose uptake; insulin resistance; typ 2 diabetes; serum; VETERINARY MEDICINE Medicine; VETERINÄRMEDICIN Medicin;

    Sammanfattning : The aim of the present thesis was to further increase our understanding of mechanisms contributing to and maintaining cellular insulin resistance in type 2 diabetes (T2D). For this reason, the effects of high glucose and insulin levels on glucose transport capacity and insulin signaling, with emphasis on insulin receptor substrate 1 (IRS-1) were assessed in fat cells. LÄS MER

  2. 2. Mechanisms and Biological Costs of Bacterial Resistance to Antimicrobial Peptides

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Hava Lofton Tomenius; Dan I Andersson; Ørjan Samuelsen; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial peptides; antibiotic resistance; fitness cost; Salmonella Typhimurium; Staphylococcus aureus; bile; serum; pH response; growth rate; mice; phoP; pmrB; waaY; LPS; LL-37; defensins; membrane potential; Mikrobiologi; Microbiology;

    Sammanfattning : The global increasing problem of antibiotic resistance necessarily drives the pursuit and discovery of new antimicrobial agents. Antimicrobial peptides (AMPs) initially seemed like promising new drug candidates. Already members of the innate immune system, it was assumed that they would be bioactive and non-toxic. LÄS MER

  3. 3. Cardiovascular risk indicators in adolescents the Umeå youth study

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Erik Bergström; Lars Åke Persson; Olle Hernell; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular risk factors; adolescents; serum lipids; serum insulin; serum ferritin; anthropometry; blood pressure; physical fitness; physical activity; diet; smoking; socio-economic status;

    Sammanfattning : Atherosclerotic cardiovascular diseases (CVD), particularly coronary heart disease (CHD) and cerebrovascular disease, are today major causes of death in the industrialised parts of the world. There are evidence to suggest that the atherosclerotic process starts in childhood, implying that preventive measures should be implemented already in children and adolescents. LÄS MER

  4. 4. Magnesium and the Insulin Resistance Syndrome

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Arvo Hänni; L Resnick; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical sciences; magnesium; calcium; insuline resistance syndrome; hypertension; lipids; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Geriatrics; geriatrik;

    Sammanfattning : Insulin resistance, defined as a state of reduced insulin-mediated glucose uptake in peripheral tissues, and disorders such as obesity, hypertension, and dyslipidemia, have been found to be associated in the conglomerate of the insulin resistance syndrome. Some antihypertensive drugs have been shown to decrease insulin sensitivity further. LÄS MER

  5. 5. Muscle Morphology and the Insulin Resistance Syndrome A Population-Based Study of 70 Year-Old-Men in Uppsala

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Anu Hedman; Stevo Julius; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical sciences; Muscle morphology; fiber distribution; capillary density; insulin resistance syndrome; physical activity; hypertension; insulin-mediated blood flow; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Geriatrics; geriatrik;

    Sammanfattning : Skeletal muscle accounts for the largest part of insulin-mediated glucose uptake. Insulin resistance (IR) is the main component of insulin resistance syndrome (IRS) and is an essential cause of a number of cardiovascular risk factors. LÄS MER