Sökning: "Actin cytoskeleton regulation"

Visar resultat 26 - 30 av 54 avhandlingar innehållade orden Actin cytoskeleton regulation.

  1. 26. Regulation of phagocytosis and phagolysosome fusion in human leukocytes

    Författare :Maria Lindmark; Per-Arne Oldenborg; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Professional phagocytes such as neutrophil granulocytes and macrophages are an esential part of the innate immune system. The neutrophils form the first line of defence against invading microorganisms and are important for rapid killing of the intruders. LÄS MER

  3. 27. Regulation of VEGFR2 signaling in angiogenesis and vascular permeability

    Författare :Chiara Testini; Lena Claesson-Welsh; Mats Hellström; Mauro Giacca; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; VEGFR2; angiogenesis; permeability; NRP1; Y949; Y1212; paladin; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Angiogenesis and vascular permeability occur in physiological and pathological conditions. Angiogenesis denotes the process of blood vessel formation from preexisting quiescent vessels. LÄS MER

  4. 28. Regulation of GRAF1 membrane sculpting function during cell movement

    Författare :Monika K. Francis; Richard Lundmark; Pekka Lappalainen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocytosis; migration; polarisation; tension; CLIC GEEC; GRAF1; Rho GTPase; Cdc42; Rab8; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : All eukaryotic cells rely on endocytic events to satisfy a constant need for nutrient and fluid uptake from their surroundings. Endocytosis-dependent turnover of cell surface constituents also serves to control signal transduction and establish morphological changes in response to extracellular stimuli. LÄS MER

  5. 29. Early induced immune responses : regulation of dendritic cell and NK cell functions

    Författare :Robert Wallin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Dendritic cell; Natural killer cell; Cytoskeleton; cAMP; cytotoxicity;

    Sammanfattning : The evolution of the advanced vertebrate adaptive immune system has required co-evolution of sophisticated immune regulating systems that determine immune class of cytokines, antibodies as well as effector mechanisms used by killer cells. The co-ordination of these responses are likely to be carried out by dendritic cells (DC) under the influence of the tissue cells and innate immune cells resident in the tissue from where the DC originates. LÄS MER

  7. 30. Role of TGFβ-induced hyaluronan-CD44 signaling in cancer progression

    Författare :Constantinos Kolliopoulos; Evi Heldin; Aristidis Moustakas; Jonathan Sleeman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hyaluronan; CD44; TGFβ; cancer; EMT; signal transduction; transcriptional regulation;

    Sammanfattning : Hyaluronan, a prevalent glycosaminoglycan of the extracellular space often accumulates in pathological conditions, such as chronic inflammation, infection, and cancer. Hyaluronan synthase HAS2 has been responsible for the synthesis and deposition of hyaluronan in a variety of tumors. LÄS MER