Sökning: "Actin cytoskeleton regulation"

Visar resultat 11 - 15 av 54 avhandlingar innehållade orden Actin cytoskeleton regulation.

1. 11. Molecular regulation of epithelial tube size

   Författare :Erika Tång Hallbäck; Göteborgs universitet; []
   Nyckelord :Drosophila; tube shape; trachea; chitin; luminal matrix; epithelial tubes; morphogenesis; chloride channel; subapical actin;

   Sammanfattning : In nature, epithelial tubes are vital structures in organ design and are required for transport of gases and liquids in organs, such as the vascular system, the vertebrate lung and the kidneys. The tubular epithelium is single layered, but is often reinforced by layers of muscular support. LÄS MER

3. 12. Regulation of endothelial transport

   Författare :Shu Ming Liu; Göran K. Hansson; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : A major role of endothelial cells is to control the influx of solutes into tissues. The aim of the research presented in this thesis was to gain knowledge about the regulation of endothelial transport in relation to the structure of the endothelial cytoskeleton and to elucidate the possible mechanisms of regulation. LÄS MER

4. 13. Regulation of the cytoskeleton and the adhesiveness of intestinal epithelial cells by leukotriene D4

   Författare :Ramin Massoumi; Institutionen för translationell medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Cytology; patologisk anatomi; Patologi allmän ; pathological anatomy; General pathology; PKC; vinculin; actin filament; focal adhesion; LTD4; integrin; cancerology; Cytologi; onkologi; cancer; Biochemistry; Metabolism; Biokemi; metabolism;

   Sammanfattning : Leukotrienes belong to a family of biologically active conjugated trienes that are formed from arachidonic acid via the 5-lipoxygenase pathway and are important mediators of inflammatory reactions. The CysLT1 receptor that specifically serves as receptor for leukotriene D4 (LTD4) has been identified as a G-protein coupled receptor. LÄS MER

5. 14. Adseverin – An Immune-Specific Target of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin

   Författare :Camilla Svensson; Lars Wärngård; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Toxicology; 2; 3; 7; 8-Tetrachlorodibenzo-p-dioxin; TCDD; adseverin; aryl hydrocarbon receptor; immunotoxicity; thymus; cytoskeleton; Toxikologi; Toxicology; Toxikologi; Toxicology; toxikologi;

   Sammanfattning : The environmental pollutant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces thymus atrophy and immunosuppression in all animal species examined and these effects constitute a potential risk to humans. TCDD can via binding to the intracellular aryl hydrocarbon receptor (AhR), modulate transcription of a number of genes and the aim of this thesis has been to identify such genes, which may explain the mechanisms behind TCDD-mediated immunotoxicity. LÄS MER

7. 15. Macromolecular interactions, Consequences on carbohydrate metabolism

   Författare :Sandra Matic; Biologiska institutionen; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; macromolecular interactions; sucrose synthase; macromolecular crowding; cytoskeleton; BY-2 tobacco cells; alamethicin; aqueous polymer two-phase partitioning;

   Sammanfattning : Most cells are crowded with solutes, enzymes, nucleic acids, structural proteins and membranes. Crowding promotes macromolecular interactions and determines major properties of the cellular environment such as viscosity, diffusion and inhomogeneity. LÄS MER