Sökning: "Constantinos Kolliopoulos"

Hittade 1 avhandling innehållade orden Constantinos Kolliopoulos.

1. 1. Role of TGFβ-induced hyaluronan-CD44 signaling in cancer progression

   Författare :Constantinos Kolliopoulos; Evi Heldin; Aristidis Moustakas; Jonathan Sleeman; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hyaluronan; CD44; TGFβ; cancer; EMT; signal transduction; transcriptional regulation;

   Sammanfattning : Hyaluronan, a prevalent glycosaminoglycan of the extracellular space often accumulates in pathological conditions, such as chronic inflammation, infection, and cancer. Hyaluronan synthase HAS2 has been responsible for the synthesis and deposition of hyaluronan in a variety of tumors. LÄS MER