Sökning: "90Y"

Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet 90Y.

  1. 1. Determination of Sr-90 in environmental samples

    Författare :Ingvar Friberg; Chalmers tekniska högskola; []
    Nyckelord :90Sr; fission products; environment; 89Sr; leaching; Cherenkov radiation; solvent extraction; 90Y;

    Sammanfattning : .... LÄS MER

  3. 2. Activity quantification based on scintillation camera imaging - Application to 111In/90Y radioimmunotherapy

    Författare :David Minarik; Lund Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radioimmunotherapy; bremsstrahlung imaging; activity quantification; SPECT; conjugate view; Yttrium;

    Sammanfattning : Radionuclide therapy (RNT), is important for the treatment of certain benign and malignant diseases. 90Y-Zevalin™ therapy has become an established method of treating patients with non-Hodgkin B-cell lymphoma. LÄS MER

  4. 3. RADIOIMMUNOTHERAPY & EXTRACORPOREAL ADSORPTION Preclinical Studies of the Pharmacokinetics & Biotinylation of Radioimmunoconjugates in Immunocompetent Rats

    Författare :Zhongmin Wang; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; onkologi; cancer; oncology; cancerology; Cytologi; Cytology; extracorporeal adsorption; tri-functional chelator; maximal tolerable dose; biotin; intraperitoneal administration; biodistribution; pharmacokinetics; biotinylation; radiolabeling; rat; monoclonal antibody; radionuclide;

    Sammanfattning : Extracorporeal adsorption (ECAT) is a novel strategy to reduce activity in whole body (WB), blood and radiosensitive organs by removing the excess of radiolabeled and biotinylated monoclonal antibody (MAb) from blood so that tumor/normal tissue ratio (T/N) could be improved. By increasing T/N, higher amounts of radiolabeled MAb might be administered, making it possible to treat disseminated carcinomas. LÄS MER

  5. 4. Targeted radionuclide therapy for patients with neuroendocrine tumours with focus on normal tissue response in 177-Lu-DOTATATE treatment

    Författare :Johanna Svensson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radionuclide therapy; Neuroendocrine tumours; 177Lu-DOTATATE; dosimetry; normal tissue response;

    Sammanfattning : Targeted radionuclide therapy with 177Lu-DOTATATE for patients with neuroendocrine tumours utilises the frequent overexpressing of somatostatin receptors on the tumour cells. This treatment modality has demonstrated valuable patient benefits and is well tolerated. However, renal and bone marrow toxicity can become dose limiting and persisting. LÄS MER

  7. 5. High-Dose Radioimmunotherapy and Extracorporeal Depletion in A Syngeneic Rat Tumor Model

    Författare :Linda Mårtensson; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : ABSTRACT Radioimmunotherapy (RIT) consists of using monoclonal antibodies (mAbs) recognizing tumor-selective antigens, as carriers of cytotoxic radionuclides to tumor tissue. RIT has been effective in lymphoma but less successful in solid tumors. LÄS MER