Sökning: "vectors"

Visar resultat 1 - 5 av 444 avhandlingar innehållade ordet vectors.

1. 1. Principal Word Vectors

   Författare :Ali Basirat; Joakim Nivre; Hinrich Schütze; Uppsala universitet; []
   Nyckelord :HUMANIORA; HUMANITIES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; word; context; word embedding; principal component analysis; PCA; sparse matrix; singular value decomposition; SVD; entropy;

   Sammanfattning : Word embedding is a technique for associating the words of a language with real-valued vectors, enabling us to use algebraic methods to reason about their semantic and grammatical properties. This thesis introduces a word embedding method called principal word embedding, which makes use of principal component analysis (PCA) to train a set of word embeddings for words of a language. LÄS MER

3. 2. Chimeric gene delivery vectors : Design, synthesis, and mechanisms from transcriptomics analysis

   Författare :Moataz Dowaidar; Ülo Langel; Sandrine Sagan; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell-penetrating peptides; magnetic nanoparticles; graphene oxide; autophagy; siRNA; SCO; QSAR; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Sammanfattning : Delivery of nucleic acid is a promising approach for genetic diseases/disorders. However, gene therapy using oligonucleotides (ONs) suffers from low transfection efficacy due to negative charges, weak cellular permeability, and enzymatic degradation. LÄS MER

4. 3. On Face Vectors and Resolutions

   Författare :Afshin Goodarzi; Anders Björner; Volkmar Welker; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : This thesis consist of the following three papers.Convex hull of face vectors of colored complexes. In this paper we verify a conjecture by Kozlov (Discrete ComputGeom18(1997) 421–431), which describes the convex hull of theset of face vectors ofr-colorable complexes onnvertices. LÄS MER

5. 4. Generation of induced neurons via direct conversion in vivo and in vitro

   Författare :Olof Torper; Neurobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cellular reprogramming; cell replacement therapies; induced dopaminergic neurons; in vivo reprogramming; Lentiviral vectors; AAV vectors;

   Sammanfattning : Cellular reprogramming is when one cell is changed into another. This involves structural modifications on the DNA of a cell resulting in a transcriptional change. This occurs naturally during development when early pluripotent cells gradually differentiate into more specialized cells that finally result in a complete organism. LÄS MER

7. 5. Alphavirus vectors as recombinant vaccines

   Författare :Peter Berglund; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Semliki Forest virus; Alphavirus; Synthetic vaccmes; Influenza A virus; HIV-I; SIV; DNA vaccines; AIDS vaccines; Influenza vaccine;

   Sammanfattning : This thesis describes further developments of an expression system based on the alphavirus Semliki Forest virus (SFV), and its potential use as recombinant vaccine. The RNA genome of SFV contains a 3'open reading frame (ORF) encoding the structural proteins, and a 5' ORF coding for the viral replicase. LÄS MER