Sökning: "SCO"

Visar resultat 1 - 5 av 10 avhandlingar innehållade ordet SCO.

1. 1. Chimeric gene delivery vectors : Design, synthesis, and mechanisms from transcriptomics analysis

   Författare :Moataz Dowaidar; Ülo Langel; Sandrine Sagan; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell-penetrating peptides; magnetic nanoparticles; graphene oxide; autophagy; siRNA; SCO; QSAR; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Sammanfattning : Delivery of nucleic acid is a promising approach for genetic diseases/disorders. However, gene therapy using oligonucleotides (ONs) suffers from low transfection efficacy due to negative charges, weak cellular permeability, and enzymatic degradation. LÄS MER

3. 2. A Study of Biomass Combustion Problems and the Selective Catalytic Oxidation of Ammonia

   Författare :Göran Olofsson; Kemiska institutionen; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Chemical technology and engineering; Kemiteknik och kemisk teknologi; Energy research; Reaction mechanism; Ammonia degradation; Pt CuO Al2O3 Catalysts; SCO; Selective Catalytic Oxidation; Catalytic hot gas cleaning; Bed agglomeration; NOx emissions; Fluidised bed; Biomass combustion; Biogas; Energiforskning;

   Sammanfattning : Increasing awareness of the need of reducing CO2, NOx and SOx emissions from combustion systems has led to a strong interest in biomass as a fuel source. Using it in combination with fluidised bed combustion technology can lead to a lowering of NOx emissions to the atmosphere. LÄS MER

4. 3. Investigations in the band-spectra of the diatomic molecules ScO, YO and LaO

   Författare :Lars Åkerlind; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : .... LÄS MER

5. 4. Rational design of novel cell-penetrating peptides

   Författare :Staffan Lindberg; Ülo Langel; Lena Mäler; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Sammanfattning : Although cell-penetrating peptides (CPPs) have been an active field of research for over 20 years there are still properties such as efficiency and stability that must be improved for CPPs to reach their full potential as delivery vectors.In this thesis two peptides were designed for non-covalent oligonucleotide delivery, in an attempt to overcome two major issues hampering wider use of CPPs, namely low stability and endosomal entrapment. LÄS MER

7. 5. Acylated cell-penetrating peptides for nucleic acid delivery

   Författare :Tönis Lehto; Ülo Langel; Eric Johnston; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cell-penetrating peptides; nucleic acid delivery; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Sammanfattning : In recent decades many new methods have been developed to cure or treat genetical disorders such as cancer, viral infections or inheritable diseases. The problem is that the nucleic acids and their synthetic analogs, oligonucleotides, are not able to cross the cell membrane due to their physicochemical properties like high negative charge and size. LÄS MER