Sökning: "Influenza vaccine"
Visar resultat 1 - 5 av 38 avhandlingar innehållade orden Influenza vaccine.
1. Influenza Neuraminidase : Conserved features of a rapidly mutating virus
Sammanfattning : Influenza A viruses (IAVs) of the H1N1 and H3N2 serotypes are the major cause of seasonal influenza epidemics. IAVs are labeled based on the antigenic properties of the two surface glycoproteins and main antigens: hemagglutinin (HA/H) and neuraminidase (NA/N). LÄS MER
2. Lung-resident, M2e-specific CD4 T cells critically protect during influenza infection
Sammanfattning : Memory CD4+ T cells are a critical component of the adaptive immune response to fight infection. However, current vaccines against influenza only focus on the other arm of adaptive immunity—triggering B cells to produce antibodies. LÄS MER
3. Broadly protective nanoparticle-based mucosal vaccine against influenza virus infection
Sammanfattning : Influenza is one of the major viral diseases affecting humans and it is responsible for three to five million cases of severe illness and about 250.000 to 500.000 deaths each year worldwide. LÄS MER
4. Liposomes for mucosal vaccine delivery: physicochemical characterization and biological application
Sammanfattning : Liposomes are attractive vaccine carriers due to their potential to act as adjuvants, and to the fact that their composition and characteristics are virtually endlessly customizable. However, the precise physicochemical profile of an ideal carrier liposome for mucosal vaccines is still widely unknown, and how different properties affect key steps in the acquisition of protective immunity remains to be elucidated. LÄS MER
5. Studying the influence of the physicochemical properties of lipid nanoparticles for mucosal vaccine delivery
Sammanfattning : Lipid-based nanoparticles have attracted attention as promising pharmaceutical carriers. Reports of them having inherent adjuvant properties make them particularly interesting as vaccine vectors; however, the physicochemical profile of an ideal nanoparticle for mucosal vaccine delivery remains unknown. LÄS MER