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Visar resultat 1 - 5 av 8 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Misoprostol : pharmacokinetics and effects on uterine contractility and cervical ripening in early pregnancy

    Författare :Annette Aronsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Misoprostol induced abortion pregnancy sublingual administration cervical ripening slow-release uterine contractility pharmacokinetics;

    Sammanfattning : Misoprostol is an orally active synthetic PGE1 analogue which has become an important drug in obstetric and gynaecological practice because of its uterotonic and cervical priming actions. It is safe, cheap, widely available and stable at room temperature. LÄS MER

  3. 2. Receptor-mediated uterine effects of oxytocin and vasopressin

    Författare :Ragner Liedman; Lund Obstetrik och gynekologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurohypophyseal; vasopressin receptor; oxytocin; pregnancy; oxytocin and vasopressin V1a antagonist; prostaglandin F2 alpha; primary dysmenorrhoea;

    Sammanfattning : The neurohypophyseal hormones oxytocin and vasopressin are important in the regulation of uterine contractility. These hormones, as well as prostaglandin F2α, are most forceful myometrial tissue contractors. LÄS MER

  4. 3. The uterine proteoglycan expression in pregnancy and labor

    Författare :Ann Hjelm Cluff; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Labor; dysfunctional labor; heparan sulphate proteoglycans; syndecans; glypicans; perlecans; decorin; connexin 43; gap junctions; myometrial contractions;

    Sammanfattning : Objective: Protracted labor is a common clinical problem causing maternal and fetal complications. It is the leading indication for caesarean sections throughout the world, and emphasizes our need to be able to control labor. LÄS MER

  5. 4. OXYTOCIN AND VASOPRESSIN IN UTERINE ACTIVITY. Receptor-mediated agonism and antagonism with special regard to the aetiology and treatment of preterm labour and primary dysmenorrhoea

    Författare :Thomas Bossmar; Lund Obstetrik och gynekologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics; primary dysmenorrhoea.; preterm labour; vasopressin antagonist; receptors; oxytocin antagonist; vasopressin; Oxytocin; gynaecology; andrology; reproduction; sexuality; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet;

    Sammanfattning : With a view to the aetiology and treatment of preterm labour and primary dysmenorrhoea we studied the influence of sexual steroids on the plasma levels of oxytocin and vasopressin, effect of these peptides on uterine contractility in vitro and in vivo, receptor concentrations and antagonists to oxytocin and vasopressin. In postmenopausal women oestrogen increased the concentrations in plasma of both peptides, whereas progesterone increased oxytocin but decreased vasopressin levels. LÄS MER

  7. 5. Improving medical abortion : using mifepristone in combination with a prostaglandin analogue

    Författare :Christian Fiala; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Medical abortion; mifepristone; misoprostol; slow release; home use; hCG; ultrasound; verification of expulsion; non-steroidal anti-inflammatory drug; pain relief; second trimester; uterine contractility; acceptability;

    Sammanfattning : Background: Induced abortion is still a major health problem in the world and the most frequently performed intervention in Obstetrics and Gynaecology with an estimated total of 46 millions worldwide each year. Medical abortion with mifepristone and prostaglandin was first introduced in 1988, and is now approved in 29 countries. LÄS MER