Sökning: "thromboxane"

Visar resultat 11 - 15 av 25 avhandlingar innehållade ordet thromboxane.

  1. 11. Prostaglandin E2 as mediator and modulator of airway smooth muscle responses

    Författare :Jesper Säfholm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Prostaglandin E2 (PGE2) is a lipid mediator produced by virtually every cell of the human body. Because common non-steroidal anti-inflammatory drugs (NSAIDs) inhibit its biosynthesis, PGE2 is usually considered to be a ‘pro-inflammatory’ mediator. The role of PGE2 in the lung and airways has however always been unclear. LÄS MER

  3. 12. Hydronephrosis in childhood : An experimental and clinical study

    Författare :Nils Wåhlin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Hydronephrosis; experimental ureteral obstruction; tubuloglomerular feedback; renal blood flow; vasoactivre substances; pressure flow measurement; Kirurgi; Surgery; Kirurgi; kirurgi; särskilt barnkirurgi; Pediatric Surgery;

    Sammanfattning : In this thesis the pathophysiology of hydronephrosis due to ureteropelvic junction (UPJ) obstruction was studied. The kidney adapts to obstruction by changes in renal blood flow (RBF) and glomerular filtration rate (GFR). LÄS MER

  4. 13. Structure and expression of the TP and EP1 prostanoid receptor genes

    Författare :Björn Båtshake; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; Neurologi; neurofysiologi; Neurology; neuropsychology; neurophysiology;

    Sammanfattning : Prostanoids are ubiquitously distributed lipid signaling molecules derived from arachidonic acid, that exhibit numerous and diverse biological effects in a variety of physiological and pathophysiological conditions. The cell surface receptors for the prostanoids belong to the family of G protein-coupled receptors. LÄS MER

  5. 14. A study on the vascular effects of prostaglandin F2α[ and latanaprost in the eye with special reference to the surface hyperaemia after topical administration

    Författare :Maria Astin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Prostaglandin F2a; Prostaglandin F2a-isopropyl ester; latanoprost; latanoprost acid; ocularhyperaemia; blood flow; sensory nerves; veins; arteries; nitric oxide; substance P; CGRP; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Pharmacognosy; farmakognosi;

    Sammanfattning : The ocular hypotensive effect of topically applied prostaglandins is usually accompanied byconjunctival hyperaemia and irritation. The purpose of the present study was to investigate thepharmacological mechanism of the ocular surface hyperaemia induced by topically appliedprostaglandins, particularly prostaglandin F2α (PGF2α) and its synthetic analogue latanoprost, aselective FP prostanoid receptor agonist. LÄS MER

  7. 15. Mechanisms of inflammatory lung injury : Studies in isolated perfused rat lungs

    Författare :Anders Ljungman; Östergötlands Läns Landsting; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Isolated perfused rat lungs (IPRLs) were used to study mechanisms andmediators of lung injury due to (i) ischemia-reperfusion (IR) and (ii) endotoxin. To investigate the role of polymorphonuclear neutrophils (PMNs) in IR injury, PMNs were added to the perfusate of IPRLs subjected to IR. LÄS MER