Sökning: "thrombospondin"

Visar resultat 1 - 5 av 28 avhandlingar innehållade ordet thrombospondin.

  1. 1. Thrombospondin 1, an autocrine regulator in T cell adhesion and migration

    Författare :ShuShun Li; Karl-Gösta Sundqvist; Jan Holgersson; Claes Dahlgren; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; T cell; adhesion; migration; thrombospondin; Immunologi; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : Lymphocytes, the principal cells of the immune system, perform the immune function throughout the body by their unique capacity to circulate in blood stream and lymphatic vessels and migrate in lymphoid and non-lymphoid tissues. The mechanisms regulating lymphocyte adhesion and migration, interactions with cells and components within the extracellular matrix are not fully understood. LÄS MER

  3. 2. Binding of plasma proteins by Staphylococcus epidermidis: characterisation of protein-protein interactions

    Författare :Dai-Qing Li; Diabetes - öpatofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; mice and immunisation; biomaterial-associated infections; von Willebrand factor; thrombospondin; clusterin; Staphylococcal receptins; vitronectin; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Coagulase-negative staphylococci (CoNS), in particular, Staphylococcus epidermidis, have emerged as major nosocomial pathogens associated with infections of implanted medical devices. These organisms, which are among the most prevalent bacteria of the human skin and mucous membrane microflora, gain access to the surface of the implant at the insertion. LÄS MER

  4. 3. Role of Thrombospondin-1 in Endogenous and Transplanted Pancreatic Islets

    Författare :Johan Olerud; Per-Ola Carlsson; Nils Welsh; Leif Jansson; Thierry Berney; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical cell biology; Medicinsk cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : Type 1 diabetes mellitus is a severe life-long disease with a pronounced risk of developing secondary complications. One way to avoid the latter is to restore the fine tuning of blood glucose homeostasis by transplantation of pancreatic islets. LÄS MER

  5. 4. Endogenous thrombospondin-1 and proteases in the regulation of lymphocyte adhesion and motility

    Författare :Anna Forslöw; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The human immune system, which protects the body from invading pathogens, largely depends on the proper function of lymphocytes, which are highly motile and constantly recirculate the blood and lymph. Adhesive and motile capability is often amplified or uncontrolled during chronic inflammatory conditions such as autoimmune diseases. LÄS MER

  7. 5. Pathogenesis of infections related to foreign devices within the cerebral ventricles

    Författare :Fredrik Lundberg; Avdelningen för medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteriology; Microbiology; CSF-shunt; complement activation; vitronectin; hydrocephalus; coagulase-negative staphylococci; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Coagulase-negative staphyloccoci (CoNS) are the most frequently isolated micro-organisms from infected cerebrospinal fluid (CSF) shunts and temporary ventricular drainage catheters, used in modern neurosurgery. CoNS originate from the skinflora of the patient or the surgeon and gain access to the surface of the implant at the insertion, but the infection can erupt up to a year later or more. LÄS MER