Sökning: "synapses"

Visar resultat 31 - 35 av 133 avhandlingar innehållade ordet synapses.

  1. 31. Role of Endogenous BDNF and NT3 for Synaptic Transmission and Plasticity in the Dentate gyrus

    Författare :Klara Olofsdotter; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hippocampus; dentate gyrus; GABA; glutamate; synaptic transmission; synaptic plasticity; Brain-derived neurotrophic factor; neurotrophin 3; Neurologi; neurophysiology; neuropsychology; Neurology; electrophysiology; neurofysiologi; neuropsykologi;

    Sammanfattning : The neurotrophins, notably brain-derived neurotrophic factor (BDNF) and neurotrophin 3 (NT3), modulate synaptic transmission and synaptic plasticity in the adult mammalian brain. Recent data suggest that neurotrophins might be mediators of activity-dependent synaptic plasticity. LÄS MER

  3. 32. The central cervical nucleus in the rat : studies on connectivity, function and chemical transmission

    Författare :Birger Ragnarson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Amino acid transmitter AMPA Anterograde Cerebellum Cervical Choleragenoid Electron microscopy Freeze-substitution Glutamate Horseradish peroxidase Ia primary afferent Immunogold Immunocytochemistry Locomotion Motoneuron NMDA Neck muscle Postembedding;

    Sammanfattning : The central cervical nucleus (CCN) is a spinocerebellar cell group in the upper cervical spinal cord (rat: Cl-C3), that is known to receive a powerful primary afferent input from, the upper cervical spinal nerves (C 1-C4), originating mainly from muscle spindle afferents in deep dorsal neck muscles and from the ipsi- and contralateral vestibular nuclei. It projects to the cerebellar vermis bilaterally and to all the vestibular nuclei contralaterally. LÄS MER

  4. 33. Studies of amyloid precursor protein trafficking and processing

    Författare :Shaohua Xu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Alzheimer’s disease (AD) is the most common form of neurodegenerative disease that slowly impairs memory and thinking abilities. Abnormal accumulation and aggregation of amyloid β peptides (Aβ), derived from proteolytic cleavage of the amyloid precursor protein (APP), is thought to be one of the critical triggers in the pathogenesis. LÄS MER

  5. 34. Studies on neuronal signaling in the hippocampus related to development, pathogenesis and treatment of mood disorders

    Författare :Nermin Sourial-Bassillious; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Hippocampus;

    Sammanfattning : The hippocampus is a central organ in the brain which is interconnected with different cortical regions and plays an important role in memory and learning processes. The anatomical position of the hippocampus together with the special sensitivity of its neurons renders it vulnerable to brain injury. LÄS MER

  7. 35. The Role of Reactive Astrocytes in Brain Ischemia and Neurotrauma

    Författare :Lizhen Li; Göteborgs universitet; []
    Nyckelord :astrocytes; intermediate filaments; GFAP; vimentin; reactive gliosis; brain ischemia; neurotrauma;

    Sammanfattning : Astrocytes are the most abundant cell type in the central nervous system (CNS) and increasing evidence now suggests that they play an active role in various brain functions. Astrocytes are involved in the induction and maintenance of the blood brain barrier, as well as the induction and stabilization of neuronal synapses. LÄS MER