Sökning: "sugar transporter"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden sugar transporter.

  1. 1. The molecular basis for substrate recognition and gating in sugar transporters

    Författare :Sarah McComas; David Drew; Philip Biggin; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; membrane transport; sugar transporter; simulations; lipids; antimalarial drugs; biokemi; Biochemistry;

    Sammanfattning : Sugar is a vital sustenance for most forms of life. For a cell to take up sugar, specialized transport proteins embedded into the membrane bilayer known as sugar porters, are required. LÄS MER

  3. 2. Establishing the mechanistic basis of sugar transport

    Författare :Abdul Aziz Qureshi; David Drew; Magnus Wolf-Watz; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; membrane transport; transport energetics; nucleotide-sugar transporters; glucose transporters; malaria; cancer; Biochemistry; biokemi;

    Sammanfattning : Sugar is a vital molecule required for cell viability and homeostasis. Sugar is important for metabolic energy, energy storage, signaling, structure and osmolyte regulation. Transport of sugar represents an important physiological process. LÄS MER

  4. 3. Determining Ligand- and Lipid- Interactions of SLC Transporters

    Författare :Yurie Chatzikyriakidou; David Drew; Robert Fredriksson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Solute carrier transporter; nucleotide-sugar transporter; SLC35; sodium proton exchanger; SLC9B2; thermal stability assay; membrane transport; Synaptic vesicle protein 2; Biochemistry; biokemi;

    Sammanfattning : Solute carrier transporters (SLCs) mediate the inter- and intra- cellular trafficking of a plethora of substrates and are essential to cell homeostasis. Despite their importance to human physiology and their potential as therapeutic targets, many SLCs are considered orphans as the physiological substrate has not been experimentally determined. LÄS MER

  5. 4. Analysis of Degradation Products from Wood and Methods for Detoxification of Lignocellulose Hydrolysates

    Författare :Per Persson; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; galactoglucomannan; mass spectrometry; liquid chromatography; sugar degradation; detoxification; fermentation inhibitors; lignocellulose hydrolysates; Ethanol production; softwood; Analytical chemistry; Analytisk kemi; countercurrent supercritical fluid extraction;

    Sammanfattning : In order to produce fuel ethanol from lignocellulose, it is necessary to hydrolyse the sugar-containing constituents hemicellulose and cellulose. During acid hydrolysis, a number of compounds are formed or liberated in addition to the fermentable monomeric sugars. LÄS MER

  7. 5. Studies on cholesterol and lipoprotein metabolism : emphasis on diabetes and sugar

    Författare :Johanna Apro; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cholesterol has important functions in the body; as a precursor in the synthesis of steroid hormones and bile acids (BAs), and as a component of cellular membranes. However, an elevated level of plasma cholesterol, transported in low density lipoprotein (LDL) particles, is one of the major risk factors and causes for cardiovascular disease. LÄS MER