Sökning: "structure elucidation"

Visar resultat 6 - 10 av 65 avhandlingar innehållade orden structure elucidation.

  1. 6. Structure elucidation of O-antigen polysaccharides from Escherichia coli

    Författare :Mona Svensson; Göran Widmalm; Roland Stenutz; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi;

    Sammanfattning : .... LÄS MER

  3. 7. Structure Elucidations of Bacterial Polysaccharides using NMR Spectroscopy and Bioinformatics

    Författare :Jonas Ståhle; Göran Widmalm; Evgeny Vinogradov; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Carbohydrates; Bioinformatics; NMR Spectroscopy; Lipopolysaccharide; Glycosyltransferase; Computer-Assisted Structure Elucidation; O-antigen; Biosynthesis; Organic Chemistry; organisk kemi;

    Sammanfattning : Carbohydrates are ubiquitous components in nature involved in a range of tasks. They cover every cell and contribute both structural stability as well as identity. Lipopolysaccharides are the outermost exposed part of the bacterial cell wall and the primary target for host-pathogen recognition. LÄS MER

  4. 8. Structural and Functional Studies of Wilms Tumour Protein - WT1; Novel Insights into Functionality of Zinc Finger Proteins

    Författare :Elmar Nurmemmedov; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Naturvetenskap; Natural science; function; structure; transcription factor; cancer; affinity; kinetics; Biacore; RNA binding; DNA binding; Wilms tumour WT1 ; zinc finger;

    Sammanfattning : The molecular process under which message in DNA is relayed onto RNA is called transcription, and it accomplished through involvement of so-called transcription factors. Zinc finger proteins are one of the most abundant classes of regulatory proteins in eukaryotic cells where they play central roles in a variety of cellular activities. LÄS MER

  5. 9. Toxicometabolomics and biotransformation product screening in single zebrafish embryos

    Författare :Anton Ribbenstedt; Jonathan P. Benskin; Magnus Breitholtz; Elena Gorokhova; Emma Schymanski; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Non-target; REACH; Orbitrap; single embryo; zebrafish embryo; metabolism; high throughput; hydroxylation; glucuronidation; metabolite screening; phase I; phase II; pharmaceutical; structure elucidation; conjugation; propranolol; beta blocker; Non-targeted; toxicometabolomics; Orbitrap; single embryo; 3R; metabolomics; MoA; mode of action; zebrafish embryo; carbamazepine; biotransformation; Applied Environmental Science; tillämpad miljövetenskap;

    Sammanfattning : Over the last decade environmental agencies worldwide have escalated their work to phase out animal testing for the purposes of chemical regulation. Meanwhile the number of commercially available chemicals and the requirements for hazard assessments have both increased, creating a large need for substitution of traditional in vivo assays with in vitro tests. LÄS MER

  7. 10. Push the limitations of crystal structure determination by 3D electron diffraction : From inorganic porous materials to biomolecules

    Författare :Jingjing Zhao; Xiaodong Zou; Hongyi Xu; Tim Grüne; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; electron crystallography; 3D electron diffraction; cryo-EM specimen preparation; structure determination; porous materials; biomolecules; fysikalisk kemi; Physical Chemistry;

    Sammanfattning : Structure elucidation is fundamental to understanding the chemical and physical properties of a material. Three-dimensional electron diffraction (3D ED) has shown great power for structure determination of nanometer- or submicrometer-sized crystals that are either too small or too complex for X-ray diffraction. LÄS MER