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Visar resultat 1 - 5 av 65 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Deciphering Carbohydrate Structure : From NMR Chemical Shifts to Conformational Analysis

    Författare :Kevin M. Dorst; Göran Widmalm; Martina Delbianco; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NMR chemical shift prediction; Structural elucidation; Conformational studies; NMR spectroscopy; MD simulations; Organic Chemistry; organisk kemi;

    Sammanfattning : Carbohydrates are ubiquitous in nature and exhibit a multitude of roles. Besides nucleic and amino acids, they can be regarded as the third alphabet of life. They are used as energy source to fuel the cells, as structural building blocks and play a key role in cellular recognition processes. LÄS MER

  3. 2. Cox-2 inhibitors of natural origin : Dereplication, isolation, and structure elucidation

    Författare :Wimal Pathmasiri; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  4. 3. NMR as a tool in drug research : Structure elucidation of peptidomimetics and pilicide-chaperone complexes

    Författare :Mattias Hedenström; Jan Jan Kihlberg; Ingmar Sethson; Michael P. Williamson; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; NMR; structure calculations; peptidomimetics; desmopressin; Leu-enkephalin; chemical shift mapping; pilicides; chaperones; urinary tract infections.; Organisk kemi; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : In the last decades NMR spectroscopy has become an invaluable tool both in academic research and in the pharmaceutical industry. This thesis describes applications of NMR spectroscopy in biomedicinal research for structure elucidation of biologically active peptides and peptidomimetics as well as in studies of ligand-protein interactions. LÄS MER

  5. 4. Tales from the Sweet Side of Life : Structure and dynamics of carbohydrate-based systems

    Författare :Alessandro Ruda; Göran Widmalm; Jesús Jiménez Barbero; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; carbohydrates; nuclear magnetic resonance; molecular dynamics; glycans; conformational analysis; structure elucidation; protein-glycan interactions; Organic Chemistry; organisk kemi;

    Sammanfattning : The field of glycomics has experienced significant developments in the last few decades, revealing a profound and elaborate language behind the intrinsic complexity of the glycans structures. This ‘sugar code’ is at the basis of intercellular interaction and recognition. For this language to be understood, its chemical basis must be unveiled. LÄS MER

  7. 5. Structure elucidation of semiochemicals related to : Polygraphus poligraphus, Polygraphus punctifrons, Trioza apicalis, Whittleia retiella, Neodiprion edulicolus, Neodiprion scutellatus, Neodiprion knereri and Neodiprion virginianus

    Författare :Rizan Rahmani; Erik Hedenström; Dan Bylund; Mittuniversitetet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Pheromone; semiochemicals; bark beetles; pest; Polygraphus poligraphus; Polygraphus punctifrons; Trioza apicalis; Whittleia retiella; Neodiprion spp.; analysis;

    Sammanfattning : .... LÄS MER