Sökning: "propranolol"

Visar resultat 1 - 5 av 39 avhandlingar innehållade ordet propranolol.

  1. 1. Enantioselective Binding of Designed Propranolol Analogues to the Cellobiohydrolase Cel7A

    Detta är en avhandling från Organic Chemistry, Lund University

    Författare :Alexandra Fagerström; Lunds universitet.; Lund University.; [2006]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Strukturkemi; Structure chemistry; enzymologi; Proteiner; enzymology; Proteins; Naturvetenskap; Natural science; capillary electrophoresis; chiral recognition; enantiomeric selectivity; cellobiohydrolase Cel7A; propranolol; Organic chemistry; Organisk kemi;

    Sammanfattning : This thesis describes the affinity and enantiomeric selectivity of the cellobiohydrolase Cel7A (isolated from Hypocrea jercorina). The chiral recognition of the enzyme has been studied with respect to amino alcohols and new ligands have been designed, based on the structure of the common ?-blocker propranolol. LÄS MER

  2. 2. Stereoselective Transport of Drugs Across the Blood-Brain Barrier (BBB) In Vivo and In Vitro Pharmacokinetic and Pharmacodynamic Studies of the (S)- and (R)-Enantiomers of Different 5-HT1A Receptor Agonists and Antagonists

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Hongmei Yan; Uppsala universitet.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; pindolol; propranolol; 2- di-n-propylamino tetralin; racemate; enantiomer; drug distribution; brain; rat; blood-brain barrier; Neurovetenskap; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Neurology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Neurologi; Psychiatry; psykiatri;

    Sammanfattning : Delivery of drugs to the brain requires passage across the blood-brain barrier (BBB). Both for drugs already on the market and for new drugs under development, it is important to know to what extent a drug enters the CNS. Many drugs used clinically are racemic mixtures, i.e. LÄS MER

  3. 3. Nano- and Micro-sized Molecularly Imprinted Polymer Materials for Analytical Application

    Detta är en avhandling från Pure and Applied Biochemistry, Lund University

    Författare :Keiichi Yoshimatsu; Lunds universitet.; Lund University.; [2008]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; spin-coating; solid-phase extraction; composite; electrospinning; precipitation polymerisation; Enkephalin; fluorescent labelling; propranolol; nanoparticles; scintillation proximity assay; Molecular imprinting; Molecularly imprinted polymers; nanofibers; thin-film; microspheres;

    Sammanfattning : Specific molecular recognition materials are important in analytical applications. It has been a longstanding dream for scientific explorers to realise a versatile method to generate materials that can recognize biological and chemical substance of interests. LÄS MER

  4. 4. Psychotropic Pharmaceuticals in Aquatic Systems: An Ecological Perspective

    Detta är en avhandling från Department of Biology, Lund University

    Författare :Melanie Hedgespeth; Lunds universitet.; Lund University.; [2015]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ecotoxicology; aquatic; trophic level; pharmaceutical; SSRI; beta-blocker; sertraline; fluoxetine; propranolol; fish; daphnia; snail; predator; prey; behavior; life history; multiple stressor;

    Sammanfattning : Popular Abstract in English Psychotropic pharmaceuticals include various groups of chemicals that have been designed to affect neurochemistry in human consumers resulting in changes in cognition, mood, and/or behavior; many target specific receptors and subsequently alter neurotransmitter levels in the central nervous system. The use of pharmaceuticals by consumers results in the release of these active substances and their breakdown products into the environment, the main source of which is through domestic wastewater treatment plants connected to households. LÄS MER

  5. 5. Bioelectronic Nanosensor Devices for Environmental and Biomedical Analysis

    Detta är en avhandling från Tryckeriet i E-huset, Lunds universitet

    Författare :Klas Risveden; Lunds universitet.; Lund University.; [2008]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Regional Ion Sensitive Field Effect Transistor; Region Ion Sensitive Field Effect Transistor; RISFET; Conducting channel; Bioelectronic Nanosensor; Bioelectronic; Biosensor; Nanosensor; Chemical Sensor; Sensor; Semiconductor sensor; Single molecule trapping; Scaling; Protein trapping; Nanoelectronics; Lab-on-a-chip; pico-ammeter; Nanobiosensor; Sample Applicator; Sequential Batch Analysis; Sequential Batch Analysis System; SBAS; Nanowire; Branched nanowire structure; Nanotree; Nanorod; Nano processing; Micro processing; Electron Beam Lithography; EBL; UV-lithography; Molecular Imprinting; DUV-lithography; Moleculary Imprinted Polymers; MIP; Biomimetics; QCM; Biomimetic sensor; Quartz Crystal Microbalance; QCM-D; Nanoparticles; Acetylcholine esterase; Glucose oxidase; Glucose; Gluconolactone; Propranolol; Gluconate; Carbofuran; Neurotoxic; Environmental analysis; Biomedical Analysis; Biotechnology; Medicine; Pesticide; Food Technology; Analyis; Flow Injection Analysis; FIA; Scanning Probe Microscopy; Scanning Kelvin Probe Microscopy; SPM; KPM; AFM; SKM; KPFM; SKPM; Nanostructures.; Atomic Force Microscopy; KFM;

    Sammanfattning : Popular Abstract in Swedish Idag kan vi mäta mycket låga halter av gifter i t. ex. dricksvatten och livsmedel, bland annat genom utvecklingen av nanosensorer. Sensorerna kan också använda's medicinskt, t. LÄS MER