Sökning: "statin"

Visar resultat 21 - 25 av 66 avhandlingar innehållade ordet statin.

  1. 21. Following the mevalonate pathway to bone heal alley

    Författare :Björn Skoglund; Lars Nordsletten; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Bone screws; coated materials; biocompatible; chemistry; diphosphonates; pharmacology; Equipment failure analysis methods; Femoral fractures; drug therapy; fracture fixation; instrumentation; Fracture fixation; fracture healing; drug effects; simvastatin; tibial fractures; physiopathologyial fractures; surgery; Pharmaceutical chemistry; Farmaceutisk kemi; Other veterinary medicine; Övrig veterinärmedicin;

    Sammanfattning : The mevalonate pathway is an important biosynthetic pathway, found in all cells of virtually all known pro- as well as eukaryotic organisms. This thesis is an investigation into the use of two drugs, originally developed for different applications, but both affecting the mevalonate pathway, in to models of fracture repair. LÄS MER

  3. 22. Improving outcome in acute myocardial infarction

    Författare :Ulf Stenestrand; Ulf de Faire; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Background: Despite common guidelines there are vanatlons in the treatment of acute myocardial infarction (AMI) between hospitals in Sweden. Uncertainties remain regarding the efficacy of early statin therapy and early revascularisation in AMI patients. In the elderly patients also the role of fibrinolytic therapy has been questioned. LÄS MER

  4. 23. On Brain Oedema

    Författare :Mårten Jungner; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatic brain injury; brain oedema; fluid therapy; blood-brain barrier;

    Sammanfattning : Traumatic brain injury and bacterial meningitis may at a glance appear as two different disease entities. The host reaction, however, to both trauma and infection involves a strong inflammatory response, with the classical symptomology of rubor, tumor, calor, dolor et functio laesa. LÄS MER

  5. 24. Targeting the role of statins in breast cancer – through translationally edged clinical trials

    Författare :Maria Feldt; Bröstcancer - prevention & intervention; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : AbstractBreast cancer incidence is increasing, and despite major progress in the treatment, breast cancer is still the leading cause of death from cancer among women. Thus, there is a constant need for new treatment options. LÄS MER

  7. 25. Clinical and Biological Factors Related to Survival in Patients with Rectal Cancer

    Författare :Angeliki Kotti; Xiao-Feng Sun; Annica Holmqvist; Marie-Louise Lydrup; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Age; Radiotherapy; Rectal cancer; Skeletal muscle; SPARCL1; Statins; Survival; Visceral adipose tissue;

    Sammanfattning : Rectal cancer is a common malignancy within the gastrointestinal tract. Despite the advances in diagnosis and treatment of rectal cancer patients during the last decades, there are still many patients who die from their disease. LÄS MER