Sökning: "statin"

Visar resultat 6 - 10 av 66 avhandlingar innehållade ordet statin.

1. 6. Mortality in Oxygen-Dependent Chronic Obstructive Pulmonary Disease and Possibilities for Pharmacological Interventions

   Författare :Magnus Ekström; allergologi och palliativ medicin Lungmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; COPD; mortality; survival; comorbidity; cardiovascular disease; cardiovascular drugs; angiotensin-converting enzyme inhibitor; angiotensin receptor blocker; beta blocker; statin; aspirin; antiplatelet drug; gender; sex; oxygen-dependent; LTOT; trends; excess mortality; SMR; hypoxemia; hypoxia; hypoxaemic;

   Sammanfattning : Background Chronic obstructive pulmonary disease (COPD) is a major and rising cause of mortality worldwide, especially in women. Patients with chronic hypoxia owing to COPD are treated with long-term oxygen therapy (LTOT) but have high morbidity and mortality. LÄS MER

3. 7. The Role of Chlamydophila Pneumoniae in the Inflammatory Response and Expansion of Abdominal Aortic Aneurysms

   Författare :Lars Karlsson; Håkan Pärsson; David Bergqvist; Janet Powell; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Abdominal aortic aneurysm; Chlamydophila pneumoniae; inflammation; aspirin; statin; expansion; randomised clinical trial; Vascular surgery; Kärlkirurgi; Surgery; kirurgi;

   Sammanfattning : Abdominal aortic aneurysm (AAA) is a common disease that develops gradually over several years and is characterised by weakening and dilatation of the aortic wall. AAAs also demonstrates a marked inflammatory infiltrate throughout the aortic wall. Chlamydophila pneumoniae (C. pneumoniae), is a common bacterium. LÄS MER

4. 8. Synthesis of bioactive natural products and analogues

   Författare :Dan Killander; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; SAR; natural product; total synthesis; benzochromene; fluorene; cannabinoid; statin; TRPA1; TSLP; antiprotozoal; nociception; asthma; inflammation;

   Sammanfattning : Natural products have until recently provided the only remedy for treatment of diseases. The development of modern chemistry in the last centuries has opened the door for tapping into the chemical diversity found in nature. Synthetic natural products, together with analogues, are an important piece in the puzzle towards curing many ailments. LÄS MER

5. 9. IgA Nephropathy – Mucosal Immunity and Treatment Options

   Författare :Hilde Kloster Smerud; Bengt Fellström; Gudjon Kristjansson; Roger Hällgren; Johan W. de Fijter; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IgA nephropathy; mucosal immunity; gastrointestinal sensitivity; food allergens; pharmacological treatment; budesonide; statin; clinical trial; renal transplantation; recurrence; Internal Medicine; Internmedicin;

   Sammanfattning : In the present studies we have explored the link between food hypersensitivity and IgA nephropathy (IgAN) and evaluated treatment options in primary and recurrent disease. Approximately one third of our IgAN patients had a rectal mucosal sensitivity to gluten, as demonstrated by increased local mucosal nitric oxide production and/or myeloperoxidase release after gluten challenge. LÄS MER

7. 10. Statin-induced cellular effects mediated by the P2X7 receptor

   Författare :Oras Mistafa; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Cholesterol-lowering statins have been shown to inhibit growth of different cancer cells both in vitro and in vivo. Epidemiological studies also indicate a chemopreventive effect of statins. We have investigated the effect of statins on Akt/protein kinase B signaling and their sensitizing effect of cytostatic drugs. LÄS MER