Sökning: "statin"

Visar resultat 16 - 20 av 66 avhandlingar innehållade ordet statin.

  1. 16. Posttransplantational bone disease : the effect of immunosuppressive drugs on bone : clinical and experimental studies

    Författare :Mohamed Mohamed Abdelhadi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Liver transplantation; hyperparathyroidism; bone density; renal transplantation; cyclosporine; prednisolone; tacrolimus; statin; growth plate; rats;

    Sammanfattning : Osteoporosis and pathologic fractures are frequent complications ill patients with end-stage liver or kidney diseases. Although successful transplantation eliminates some factors related to poor organ function, all increased incidence of pathologic fractures was reported ill the early post-transplant period in spite of normalization of the allograft function. LÄS MER

  3. 17. Power of the Pill : Views about Cardiovascular Risk and the Risk-reducing Effect of Statins

    Författare :Per Lytsy; Ragnar Westerling; Gunilla Burell; Arne Melander; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Statins; lipid-lowering drugs; cholesterol; treatment expectations; beliefs; adherence; health behaviour; Social medicine; Socialmedicin; Community pharmacy services; Samhällsfarmaci; Family medicine; Allmänmedicin; Public health science; Folkhälsovetenskap; Community medicine; Samhällsmedicin; Social Medicine; Socialmedicin;

    Sammanfattning : Medical treatments with statins are prescribed to patients with increased risk of cardiovascular events. The benefits from statin treatment are well documented in clinical trials, but long-term adherence in patients is low, indicating that patients have an uncertainty about the necessity and benefits of treatment. LÄS MER

  4. 18. Inhibition of the mevalonate pathway in C. elegans: Consequences and implications

    Författare :Parmida Ranji; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mevalonate pathway; C. elegans; atfs-1; mitochondrial unfolded response UPR ;

    Sammanfattning : The mevalonate pathway in human is responsible for the synthesis of cholesterol and other important biomolecules such as coenzyme Q (a component of the electron transport chain in mitochondria), dolichols (important for N-linked glycosylation of proteins) and isoprenoids (important for the membrane association of small GTPases). This thesis concerns novel findings about the effect of statin on the mevalonate pathway using C. LÄS MER

  5. 19. Cholesterol metabolism in breast cancer: Prognostic factors and optimizing treatment

    Författare :Maria Inasu; Bröstcancer - prevention & intervention; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Statins; Cholesterol; menopausal status; endocrine treatment; disease recurrence;

    Sammanfattning : AbstractBreast cancer (BC) is the most common cancer among women in Sweden and worldwide. Adjuvant endocrine therapies are effective, yet 20-30% patients experience disease relapse. Altered cholesterol metabolism is an emerging hallmark of breast cancer proliferation and endocrine therapy resistance. LÄS MER

  7. 20. Common medications in the risk and prognosis of lymphoid neoplasms and epidemiology of primary CNS lymphoma

    Författare :Elsa Brånvall; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Lymphoid neoplasms are malignancies arising from the lymphocyte, and include lymphoma subtypes, chronic lymphocytic leukemia (CLL) and multiple myeloma (MM). It is a heterogenous group of diseases, with different molecular pathogenesis, clinical characteristics, treatments and outcome. LÄS MER