Sökning: "diphosphonates"

Hittade 2 avhandlingar innehållade ordet diphosphonates.

1. 1. Following the mevalonate pathway to bone heal alley

   Författare :Björn Skoglund; Lars Nordsletten; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Bone screws; coated materials; biocompatible; chemistry; diphosphonates; pharmacology; Equipment failure analysis methods; Femoral fractures; drug therapy; fracture fixation; instrumentation; Fracture fixation; fracture healing; drug effects; simvastatin; tibial fractures; physiopathologyial fractures; surgery; Pharmaceutical chemistry; Farmaceutisk kemi; Other veterinary medicine; Övrig veterinärmedicin;

   Sammanfattning : The mevalonate pathway is an important biosynthetic pathway, found in all cells of virtually all known pro- as well as eukaryotic organisms. This thesis is an investigation into the use of two drugs, originally developed for different applications, but both affecting the mevalonate pathway, in to models of fracture repair. LÄS MER

3. 2. Influence of extrinsic factors on bone scintigraphy an experimental and clinical study

   Författare :Marika Cronhjort; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Bone scintigraphy; bisphosphonates; biodistribution; animal;

   Sammanfattning : Bone scintigraphy takes advantage of the strong affinity of technetiated diphosphonates to bone. These compounds accumulate particularly at sites of new bone formation which occurs as a response to various conditions affecting bone. LÄS MER