Sökning: "single particle dissolution"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden single particle dissolution.

  1. 1. Novel and refined small-scale approaches to determine the intrinsic dissolution rate of drugs

    Författare :Sara B. E. Andersson; Göran Alderborn; Göran Frenning; Peter Langguth; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dissolution; intrinsic dissolution rate; poorly water-soluble compounds; single particle dissolution; solubility; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Many drugs are administered as crystalline particles compressed into tablets and taken orally. When the tablet reaches the gastrointestinal tract, it disintegrates and the drug particles dissolve in the gastrointestinal fluid. The dissolved molecules are absorbed across the intestinal membranes into the bloodstream to reach their target sites. LÄS MER

  3. 2. New single particle methods for detection and characterization of nanoparticles in environmental samples

    Författare :Jani Tuoriniemi; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Nanoparticles; Detection; Quantification; Metrology; Trace particle;

    Sammanfattning : Nanoparticles (NP) are being used in rapidly increasing quantities which has resulted in concerns about possible harmful effects for health and environment. NP are already undergoing similar risk assessment programs as conventional chemicals, and due to their enhanced surface reactivities it has been proposed that the use of NP should be regulated by specific legislation based on particle size. LÄS MER

  4. 3. Aqueous Processing of WC-Co Powders

    Författare :Karin M. Andersson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hard Metal; Cemented Carbide; WC-Co; Tungsten Carbide; Cobalt; Oxidation; Dissolution; Surface Complexation; XPS; AFM; Colloidal Probe; Hamaker Constant; Cauchy; WO3; CoOOH; ESCA; Zeta-Potential; Surface Potential; Poly ethylene imine ; PEI; Suspensi;

    Sammanfattning : The object of this work is to obtain a fundamentalunderstanding of the principal issues concerning the handlingof an aqueous WC-Co powder suspension.The WO3 surface layer on the oxidised tungsten carbidepowder dissolves at pH>3 with the tungsten concentrationincreasing linearly with time. LÄS MER

  5. 4. Fluid and Solid Particle Dynamics in Stirred Vessels

    Författare :Mattias Ljungqvist; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mixing time; pitched blade turbine; impeller modelling; stirred vessels; computational fluid dynamics; multi-fluid model; suspension of solids; phase-Doppler anemometry; laser Doppler anemometry; closed vessels;

    Sammanfattning : The present thesis deals with the fluid dynamics of stirred vessels and particularly those that are to be used in conjunction with solids suspensions. Stirred vessels are very common in the process industry and large amounts of energy can be saved by optimising their operation. LÄS MER

  7. 5. Exploring the Molecular Dynamics of Proteins and Viruses

    Författare :Daniel Larsson; David van der Spoel; Modesto Orozco; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; molecular dynamics; virus dynamics; capsid dissolution; satellite tobacco necrosis virus; satellite tobacco mosaic virus; virus genome structure; gas phase protein structure; water layer; micelle embedded protein; membrane protein; Chemistry with specialization in Biophysics; Kemi med inriktning mot biofysik;

    Sammanfattning : Knowledge about structure and dynamics of the important biological macromolecules — proteins, nucleic acids, lipids and sugars — helps to understand their function. Atomic-resolution structures of macromolecules are routinely captured with X-ray crystallography and other techniques. LÄS MER