Sökning: "rafts"

Visar resultat 1 - 5 av 40 avhandlingar innehållade ordet rafts.

  1. 1. Distribution of glycosphingolipids in nervous tissue. Immunohistochemical and biochemical studies

    Författare :Marie Molander-Melin; Göteborgs universitet; []
    Nyckelord :Glycosphingolipids; sulfatide; nervous tissue; immunohistochemical analyses; ; biochemical analyses; rafts.;

    Sammanfattning : Glycosphingolipids (GSLs) are highly enriched in cell membranes of the mammalian nervous system. Their biological functions are not clarified although recent findings have supported their existence in plasma membrane domains, enriched in cholesterol, sphingomyelin and GSLs. LÄS MER

  3. 2. Localisation of Fluorescent Probes and the estimation of Lipid Nanodomain sizes by modern fluorescence techniques

    Författare :Radek Sachl; Lennart B-Å Johansson; Martin Hof; Mats Almgren; Tomas Obsil; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Electronic energy transfer; fluorescence; rafts; lipid bilayer; bicelles; micelles; fysikalisk kemi; Physical Chemistry;

    Sammanfattning : The thesis is divided into two major parts. The first part focuses on the localisation of probes in lipid/polymeric bilayers and in GM1 micelles. Included in this thesis is a new approach based on electronic energy transfer/migration (FRET/DDEM), which efficiently determines transversal positions of fluorescent molecules in lipid bilayers. LÄS MER

  4. 3. Membrane rafts and its GPI anchored complement inhibitors regulate insulin secretion

    Författare :Vini Nagaraj; Diabetes - öpatofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Membrane rafts; basal insulin secretion; regulated insulin secretion; CD59; CD55; SNARE proteins; insulin; pancreatic beta cells.;

    Sammanfattning : Type 2 diabetic patients usually exhibit an abnormal lipid profile. One such lipid that is constantly elevated in T2D is cholesterol. At the cellular level, cholesterol aids in tight packing of sphingolipids in certain regions of the plasma membrane and these specialized regions are termed ‘membrane rafts’, which act as signalling hubs. LÄS MER

  5. 4. Membrane Proteins in Human Neutrophils - Identification and Characterization of Lipid Rafts in Subcellular Organelles

    Författare :Elisabeth Feuk-Lagerstedt; Göteborgs universitet; []
    Nyckelord :Human neutrophils; Subcellular organelles; Membrane proteins; Lipid rafts; DRMs;

    Sammanfattning : The human neutrophil is an important effector cell in acute inflammation and in the innate immune response against bacteria and fungi. When immune reactions occur in the tissue in response to antigen challenge, neutrophils are the first cells to enter the site of inflammation. LÄS MER

  7. 5. Leukocyte responses to pathogens : integrins, membrane rafts and nitric oxide

    Författare :Martin Winberg Tinnerfelt; Birgitta Rasmusson; Maria Lerm; Eva Särndahl; Hans Tapper; Håkan Eriksson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Sammanfattning : During microbial invasion, leukocytes of the innate immunity are rapidly recruited to the site of infection where they internalize (phagocytose), kill and digest the invaders. To aid this process, leukocytes express surface receptors such as Toll-like receptors, β2-integrins and Fc-receptors. LÄS MER